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- W2161929150 abstract "In the Japanese population, sporadic late-onset Alzheimer's disease (LOAD) cases had significantly higher frequencies of the A allele of alpha 1-antichymotrypsin (ACT) gene as well as the epsilon 4 allele of apolipoprotein E (APOE) gene than controls. The odds ratio for LOAD in APOE4 carriers with the ACT-A allele was more than six times that in APOE4 carriers without the ACT-A allele (21.1 vs 3.2). These results indicate that the ACT-A allele is a risk modifier for LOAD in APOE4 carriers." @default.
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- W2161929150 date "1997-07-01" @default.
- W2161929150 modified "2023-10-10" @default.
- W2161929150 title "?1-Antichymotrypsin as a risk modifier for late-onset Alzheimer's disease in Japanese apolipoprotein E ?4 allele carriers" @default.
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- W2161929150 doi "https://doi.org/10.1002/ana.410420118" @default.
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