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• W2162061192 abstract "The causal attribution of depressive patients in negative events was significantly important. However, few previous studies have explored its neural underpinnings. The current study examines the neural basis of causal attribution in negative events of depressed patients (12) compared with healthy controls (12) by using the Attribution Style Task (AST). Briefly, participants were presented with 80 sentences describing 40 positive and 40 negative social events. Participants were asked to imagine the event happening to them and select the most likely cause with a button press: 1 self (internal), 2 another person, and 3 situation (external). Behaviorally, controls showed a self-serving bias, whereas patients demonstrated a balanced attributional pattern with the attribution scores. Our fMRI results found a significant group difference in the inferior frontal gyrus and middle temporal gyrus in depressed participants compared to normal controls. Moreover, there was a significantly increased activation in the IPL during non-self-serving attributions in negative events of patients compared to controls. Most interestingly, we also found the BOLD signal change of the region of IPL was positively related to the duration of the illness of the patients. Based on our findings, we may infer that a stronger activation of the IPL in depression may demonstrate that depressed patients always pay more attention to self-reference in negative events. These interesting findings might provide a biomarker of subtle differences in brain signal alterations associated with depressive cognitive characteristics." @default.
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• W2162061192 date "2015-07-01" @default.
• W2162061192 modified "2023-10-16" @default.
• W2162061192 title "Neural correlates of causal attribution in negative events of depressed patients: Evidence from an fMRI study" @default.
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• W2162061192 doi "https://doi.org/10.1016/j.clinph.2014.10.146" @default.
• W2162061192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25487911" @default.
• W2162061192 hasPublicationYear "2015" @default.
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