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- W2162150457 abstract "The rat basolateral amygdala is important for emotional learning; this is modulated by noradrenaline and corticosterone. We report that the beta-adrenergic agonist isoproterenol markedly enhances synaptic plasticity induced in the basolateral amygdala by a weak stimulation paradigm but is ineffective with stronger protocols. Simultaneous application of corticosterone gradually reversed the facilitatory effect of isoproterenol. When corticosterone was briefly applied several hours prior to isoproterenol, facilitatory effects of the beta-agonist were entirely suppressed. This suggests that in the basolateral amygdala, beta-adrenergic influences promote synaptic plasticity; this is gradually normalized by corticosterone, preventing the network from overshooting." @default.
- W2162150457 created "2016-06-24" @default.
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- W2162150457 date "2009-02-01" @default.
- W2162150457 modified "2023-10-06" @default.
- W2162150457 title "β-Adrenergic facilitation of synaptic plasticity in the rat basolateral amygdala in vitro is gradually reversed by corticosterone" @default.
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- W2162150457 doi "https://doi.org/10.1101/lm.1272409" @default.
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