Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162195068> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2162195068 endingPage "298" @default.
- W2162195068 startingPage "290" @default.
- W2162195068 abstract "To assess the impact on healthcare resource utilization, costs, and quality of life over 15 years from 5 years of statin use in men without a history of myocardial infarction in the West of Scotland Coronary Prevention Study (WOSCOPS).Six thousand five hundred and ninety-five participants aged 45-54 years were randomized to 5 years treatment with pravastatin (40 mg) or placebo. Linkage to routinely collected health records extended follow-up for secondary healthcare resource utilization to 15 years. The following new results are reported: cause-specific first and recurrent cardiovascular hospital admissions including myocardial infarction, heart failure, stroke, coronary revascularization and angiography; non-cardiovascular hospitalization; days in hospital; quality-adjusted life years (QALYs); costs of pravastatin treatment, treatment safety monitoring, and hospital admissions.Five years treatment of 1000 patients with pravastatin (40 mg/day) saved the NHS £710 000 (P < 0.001), including the cost of pravastatin and lipid and safety monitoring, and gained 136 QALYs (P = 0.017) over the 15-year period. Benefits per 1000 subjects, attributable to prevention of cardiovascular events, included 163 fewer admissions and a saving of 1836 days in hospital, with fewer admissions for myocardial infarction, stroke, heart failure and coronary revascularization. There was no excess in non-cardiovascular admissions or costs (or in admissions associated with diabetes or its complications) and no evidence of heterogeneity of effect over sub-groups defined by baseline cardiovascular risk.Five years' primary prevention treatment of middle-aged men with a statin significantly reduces healthcare resource utilization, is cost saving, and increases QALYs. Treatment of even younger, lower risk individuals is likely to be cost-effective." @default.
- W2162195068 created "2016-06-24" @default.
- W2162195068 creator A5001791397 @default.
- W2162195068 creator A5002948449 @default.
- W2162195068 creator A5016095791 @default.
- W2162195068 creator A5033194565 @default.
- W2162195068 creator A5034412976 @default.
- W2162195068 creator A5037853560 @default.
- W2162195068 creator A5078354802 @default.
- W2162195068 creator A5088079919 @default.
- W2162195068 date "2013-07-09" @default.
- W2162195068 modified "2023-09-24" @default.
- W2162195068 title "Long-term impact on healthcare resource utilization of statin treatment, and its cost effectiveness in the primary prevention of cardiovascular disease: a record linkage study" @default.
- W2162195068 cites W1973491874 @default.
- W2162195068 cites W1981977618 @default.
- W2162195068 cites W2004117961 @default.
- W2162195068 cites W2048993684 @default.
- W2162195068 cites W2061489988 @default.
- W2162195068 cites W2103108681 @default.
- W2162195068 cites W2126874967 @default.
- W2162195068 cites W2155598961 @default.
- W2162195068 cites W2608735143 @default.
- W2162195068 cites W4241579954 @default.
- W2162195068 cites W4254615263 @default.
- W2162195068 doi "https://doi.org/10.1093/eurheartj/eht232" @default.
- W2162195068 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3909301" @default.
- W2162195068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23839541" @default.
- W2162195068 hasPublicationYear "2013" @default.
- W2162195068 type Work @default.
- W2162195068 sameAs 2162195068 @default.
- W2162195068 citedByCount "77" @default.
- W2162195068 countsByYear W21621950682013 @default.
- W2162195068 countsByYear W21621950682014 @default.
- W2162195068 countsByYear W21621950682015 @default.
- W2162195068 countsByYear W21621950682016 @default.
- W2162195068 countsByYear W21621950682017 @default.
- W2162195068 countsByYear W21621950682018 @default.
- W2162195068 countsByYear W21621950682019 @default.
- W2162195068 countsByYear W21621950682020 @default.
- W2162195068 countsByYear W21621950682021 @default.
- W2162195068 countsByYear W21621950682022 @default.
- W2162195068 countsByYear W21621950682023 @default.
- W2162195068 crossrefType "journal-article" @default.
- W2162195068 hasAuthorship W2162195068A5001791397 @default.
- W2162195068 hasAuthorship W2162195068A5002948449 @default.
- W2162195068 hasAuthorship W2162195068A5016095791 @default.
- W2162195068 hasAuthorship W2162195068A5033194565 @default.
- W2162195068 hasAuthorship W2162195068A5034412976 @default.
- W2162195068 hasAuthorship W2162195068A5037853560 @default.
- W2162195068 hasAuthorship W2162195068A5078354802 @default.
- W2162195068 hasAuthorship W2162195068A5088079919 @default.
- W2162195068 hasBestOaLocation W21621950682 @default.
- W2162195068 hasConcept C126322002 @default.
- W2162195068 hasConcept C127413603 @default.
- W2162195068 hasConcept C194828623 @default.
- W2162195068 hasConcept C2776839432 @default.
- W2162195068 hasConcept C2778163477 @default.
- W2162195068 hasConcept C2779519902 @default.
- W2162195068 hasConcept C2780645631 @default.
- W2162195068 hasConcept C500558357 @default.
- W2162195068 hasConcept C71924100 @default.
- W2162195068 hasConcept C78519656 @default.
- W2162195068 hasConceptScore W2162195068C126322002 @default.
- W2162195068 hasConceptScore W2162195068C127413603 @default.
- W2162195068 hasConceptScore W2162195068C194828623 @default.
- W2162195068 hasConceptScore W2162195068C2776839432 @default.
- W2162195068 hasConceptScore W2162195068C2778163477 @default.
- W2162195068 hasConceptScore W2162195068C2779519902 @default.
- W2162195068 hasConceptScore W2162195068C2780645631 @default.
- W2162195068 hasConceptScore W2162195068C500558357 @default.
- W2162195068 hasConceptScore W2162195068C71924100 @default.
- W2162195068 hasConceptScore W2162195068C78519656 @default.
- W2162195068 hasIssue "5" @default.
- W2162195068 hasLocation W21621950681 @default.
- W2162195068 hasLocation W21621950682 @default.
- W2162195068 hasLocation W21621950683 @default.
- W2162195068 hasLocation W21621950684 @default.
- W2162195068 hasLocation W21621950685 @default.
- W2162195068 hasOpenAccess W2162195068 @default.
- W2162195068 hasPrimaryLocation W21621950681 @default.
- W2162195068 hasRelatedWork W1980265369 @default.
- W2162195068 hasRelatedWork W2005962533 @default.
- W2162195068 hasRelatedWork W2036773140 @default.
- W2162195068 hasRelatedWork W2039228592 @default.
- W2162195068 hasRelatedWork W2075578416 @default.
- W2162195068 hasRelatedWork W2097571126 @default.
- W2162195068 hasRelatedWork W2121068351 @default.
- W2162195068 hasRelatedWork W2141923936 @default.
- W2162195068 hasRelatedWork W2524238720 @default.
- W2162195068 hasRelatedWork W3044040073 @default.
- W2162195068 hasVolume "35" @default.
- W2162195068 isParatext "false" @default.
- W2162195068 isRetracted "false" @default.
- W2162195068 magId "2162195068" @default.
- W2162195068 workType "article" @default.