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• W2162216908 startingPage "1678" @default.
• W2162216908 abstract "Hyaluronic acid (HA)-graphene oxide (GO) conjugates, with a high loading of photosensitizers (PS; Ce6), were developed as a cancer cell targeted and photoactivity switchable nanoplatform for photodynamic therapy (PDT). HA-GO conjugates with size below 100 nm were first prepared by the chemical conjugation between ADH-modified HA and fractionated GO sheets with size relevant for drug delivery. Before evaluating the drug delivery efficacies, their chemical structure, morphology, and biocompatibility were characterized by 1H NMR, UV, TGA, AFM, DLS and MTT assays. The physical adsorption of Ce6 onto HA-GO nanocarriers was mainly due to the π-π stacking as well as hydrophobic interactions. It was demonstrated by CLSM and FACS that the cellular internalization of the HA-GO/Ce6 nanohybrids was much more effective when compared with free Ce6, which was also found to be significantly influenced by the co-treatment with an excess amount of HA polymers, illustrating their active targeting to HA receptors overexpressed on cancer cells. The photoactivity of Ce6 adsorbed on HA-GO nanocarriers was mostly quenched in aqueous solution to ensure biocompatibility, but was quickly recovered after the release of Ce6 from HA-GO nanocarriers upon cellular uptake. As a result, the PDT efficiency of the HA-GO/Ce6 nanohybrids was remarkably improved ∼10 times more than that of free Ce6, as well demonstrated in both MTT and LIVE/DEAD assays." @default.
• W2162216908 created "2016-06-24" @default.
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• W2162216908 date "2013-01-01" @default.
• W2162216908 modified "2023-10-02" @default.
• W2162216908 title "Hyaluronic acid-conjugated graphene oxide/photosensitizer nanohybrids for cancer targeted photodynamic therapy" @default.
• W2162216908 cites W1596848781 @default.
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• W2162216908 cites W1976424331 @default.
• W2162216908 cites W1976787731 @default.
• W2162216908 cites W1977293747 @default.
• W2162216908 cites W1977424722 @default.
• W2162216908 cites W1977791081 @default.
• W2162216908 cites W1978656850 @default.
• W2162216908 cites W1979321972 @default.
• W2162216908 cites W1980419364 @default.
• W2162216908 cites W1985388560 @default.
• W2162216908 cites W1985771244 @default.
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• W2162216908 cites W1989037178 @default.
• W2162216908 cites W1992180725 @default.
• W2162216908 cites W1994852477 @default.
• W2162216908 cites W1995155810 @default.
• W2162216908 cites W1995705185 @default.
• W2162216908 cites W1997548436 @default.
• W2162216908 cites W2002779938 @default.
• W2162216908 cites W2008904362 @default.
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• W2162216908 cites W2015225179 @default.
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• W2162216908 cites W2017777241 @default.
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• W2162216908 cites W2022765010 @default.
• W2162216908 cites W2023538581 @default.
• W2162216908 cites W2027268803 @default.
• W2162216908 cites W2028464008 @default.
• W2162216908 cites W2032760352 @default.
• W2162216908 cites W2059227878 @default.
• W2162216908 cites W2059271554 @default.
• W2162216908 cites W2068379876 @default.
• W2162216908 cites W2068920186 @default.
• W2162216908 cites W2071167287 @default.
• W2162216908 cites W2082572892 @default.
• W2162216908 cites W2088719923 @default.
• W2162216908 cites W2091191348 @default.
• W2162216908 cites W2091285961 @default.
• W2162216908 cites W2094773533 @default.
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• W2162216908 cites W2150196271 @default.
• W2162216908 cites W2158925802 @default.
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• W2162216908 cites W2216243442 @default.
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• W2162216908 cites W2326443463 @default.
• W2162216908 cites W2328379439 @default.
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• W2162216908 doi "https://doi.org/10.1039/c3tb00506b" @default.
• W2162216908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32260699" @default.
• W2162216908 hasPublicationYear "2013" @default.
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