FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162225208> ?p ?o ?g. }

• W2162225208 endingPage "779" @default.
• W2162225208 startingPage "771" @default.
• W2162225208 abstract "Objective The aim of this study was to explore the effects of cholecalciferol supplementation on vitamin D levels, bone mineral density (BMD), body fat distribution and insulin sensitivity in vitamin D‐deficient HIV‐1‐infected patients. Methods Twenty vitamin D‐deficient HIV‐1‐infected patients were prospectively treated with 2000 IU cholecalciferol/day for 14 weeks, whereafter treatment was continued with half this dosage until 48 weeks. BMD, body fat distribution, 1,25‐dihydroxy vitamin D 3 (1,25(OH) 2 D 3 ), fasting glucose, insulin, adiponectin, leptin, interleukin (IL)‐6 and tumour necrosis factor (TNF)‐α were measured at baseline, and at 24 and 48 weeks. Parathyroid hormone (PTH), 25‐hydroxy vitamin D 3 [25(OH)D 3 ], cholesterol and triglycerides were measured at baseline, and at 12, 24 and 48 weeks. Results After 24 weeks, cholecalciferol supplementation significantly increased 25(OH)D 3 and 1,25(OH) 2 D 3 levels and decreased PTH and insulin sensitivity. After 48 weeks, however, only 25(OH)D 3 levels remained significantly different from baseline, while the other parameter levels returned to baseline, suggesting a dose–response effect. Cholecalciferol had no effect on BMD, adipokines and triglycerides. Conclusions The effect of cholecalciferol treatment in this cohort appears to be dose dependent. Cholecalciferol dosages of ≥2000 IU are necessary to achieve 1,25(OH) 2 D 3 levels that significantly decrease PTH, but also negatively affect insulin sensitivity. The results of this hypothesis‐driven explorative study need to be confirmed in larger clinical trials." @default.
• W2162225208 created "2016-06-24" @default.
• W2162225208 creator A5000396669 @default.
• W2162225208 creator A5001604373 @default.
• W2162225208 creator A5027332124 @default.
• W2162225208 creator A5032436839 @default.
• W2162225208 creator A5039138511 @default.
• W2162225208 creator A5044504157 @default.
• W2162225208 creator A5047895711 @default.
• W2162225208 creator A5061093319 @default.
• W2162225208 creator A5068183096 @default.
• W2162225208 creator A5079175535 @default.
• W2162225208 date "2008-10-01" @default.
• W2162225208 modified "2023-10-15" @default.
• W2162225208 title "The effect of cholecalciferol supplementation on vitamin D levels and insulin sensitivity is dose related in vitamin D‐deficient HIV‐1‐infected patients" @default.
• W2162225208 cites W1262585909 @default.
• W2162225208 cites W1964837255 @default.
• W2162225208 cites W1968442008 @default.
• W2162225208 cites W1968912276 @default.
• W2162225208 cites W1970359693 @default.
• W2162225208 cites W1978608905 @default.
• W2162225208 cites W1985610579 @default.
• W2162225208 cites W1990746088 @default.
• W2162225208 cites W2005026388 @default.
• W2162225208 cites W2042874806 @default.
• W2162225208 cites W2046067530 @default.
• W2162225208 cites W2057301426 @default.
• W2162225208 cites W2095287542 @default.
• W2162225208 cites W2113104444 @default.
• W2162225208 cites W2128900719 @default.
• W2162225208 cites W2139638881 @default.
• W2162225208 cites W2140504583 @default.
• W2162225208 cites W2152197563 @default.
• W2162225208 cites W2156807491 @default.
• W2162225208 cites W2158721638 @default.
• W2162225208 cites W2163810943 @default.
• W2162225208 cites W2172226708 @default.
• W2162225208 cites W4255073710 @default.
• W2162225208 doi "https://doi.org/10.1111/j.1468-1293.2008.00630.x" @default.
• W2162225208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18754805" @default.
• W2162225208 hasPublicationYear "2008" @default.
• W2162225208 type Work @default.
• W2162225208 sameAs 2162225208 @default.
• W2162225208 citedByCount "30" @default.
• W2162225208 countsByYear W21622252082012 @default.
• W2162225208 countsByYear W21622252082013 @default.
• W2162225208 countsByYear W21622252082014 @default.
• W2162225208 countsByYear W21622252082015 @default.
• W2162225208 countsByYear W21622252082016 @default.
• W2162225208 countsByYear W21622252082017 @default.
• W2162225208 countsByYear W21622252082019 @default.
• W2162225208 countsByYear W21622252082020 @default.
• W2162225208 crossrefType "journal-article" @default.
• W2162225208 hasAuthorship W2162225208A5000396669 @default.
• W2162225208 hasAuthorship W2162225208A5001604373 @default.
• W2162225208 hasAuthorship W2162225208A5027332124 @default.
• W2162225208 hasAuthorship W2162225208A5032436839 @default.
• W2162225208 hasAuthorship W2162225208A5039138511 @default.
• W2162225208 hasAuthorship W2162225208A5044504157 @default.
• W2162225208 hasAuthorship W2162225208A5047895711 @default.
• W2162225208 hasAuthorship W2162225208A5061093319 @default.
• W2162225208 hasAuthorship W2162225208A5068183096 @default.
• W2162225208 hasAuthorship W2162225208A5079175535 @default.
• W2162225208 hasBestOaLocation W21622252081 @default.
• W2162225208 hasConcept C124490489 @default.
• W2162225208 hasConcept C126322002 @default.
• W2162225208 hasConcept C134018914 @default.
• W2162225208 hasConcept C2776782570 @default.
• W2162225208 hasConcept C2776940978 @default.
• W2162225208 hasConcept C2777391703 @default.
• W2162225208 hasConcept C2779306644 @default.
• W2162225208 hasConcept C2779740938 @default.
• W2162225208 hasConcept C2780106736 @default.
• W2162225208 hasConcept C2780613262 @default.
• W2162225208 hasConcept C2781208988 @default.
• W2162225208 hasConcept C511355011 @default.
• W2162225208 hasConcept C519063684 @default.
• W2162225208 hasConcept C71924100 @default.
• W2162225208 hasConceptScore W2162225208C124490489 @default.
• W2162225208 hasConceptScore W2162225208C126322002 @default.
• W2162225208 hasConceptScore W2162225208C134018914 @default.
• W2162225208 hasConceptScore W2162225208C2776782570 @default.
• W2162225208 hasConceptScore W2162225208C2776940978 @default.
• W2162225208 hasConceptScore W2162225208C2777391703 @default.
• W2162225208 hasConceptScore W2162225208C2779306644 @default.
• W2162225208 hasConceptScore W2162225208C2779740938 @default.
• W2162225208 hasConceptScore W2162225208C2780106736 @default.
• W2162225208 hasConceptScore W2162225208C2780613262 @default.
• W2162225208 hasConceptScore W2162225208C2781208988 @default.
• W2162225208 hasConceptScore W2162225208C511355011 @default.
• W2162225208 hasConceptScore W2162225208C519063684 @default.
• W2162225208 hasConceptScore W2162225208C71924100 @default.
• W2162225208 hasIssue "9" @default.
• W2162225208 hasLocation W21622252081 @default.
• W2162225208 hasLocation W21622252082 @default.
• W2162225208 hasOpenAccess W2162225208 @default.
• W2162225208 hasPrimaryLocation W21622252081 @default.
• W2162225208 hasRelatedWork W2050931372 @default.

• next