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- W2162233488 abstract "This review deals with the excipients used in various lyophilized formulations of small molecules. The role of excipients such as bulking agents, buffering agents, tonicity modifiers, antimicrobial agents, surfactants and co-solvents has been discussed. Additionally, a decision making process for their incorporation into the formulation matrix has been proposed. A list of ingredients used in lyophilized formulations marketed in USA has been created based on a survey of the Physician Desk Reference (PDR) and the Handbook on Injectable Drugs. Information on the recommended quantities of various excipients has also been provided, based on the details given in the Inactive Ingredient Guide (IIG)." @default.
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- W2162233488 date "2010-03-01" @default.
- W2162233488 modified "2023-09-30" @default.
- W2162233488 title "Excipients used in lyophilization of small molecules" @default.
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