Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162238216> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2162238216 endingPage "576" @default.
- W2162238216 startingPage "572" @default.
- W2162238216 abstract "To investigate the incidence of adhesions after intraperitoneal instillation of mitomycin C adsorbed on activated carbon (MMC-CH). Animal and laboratory studies. University hospital, Germany. 90 Sprague-Dawley rats. Laparotomy, small bowel anastomosis, and intraperitoneal instillation of saline (controls, n = 27), activated carbon alone (n = 24) or MMC-CH (n = 26). Cultures of monolayers of human mesothelial cells. Measurements of adhesions by planimetry. Toxicity of mitomycin C alone and charcoal alone in mesothelial cell monolayers as reflected by cell proliferation and measurement of lactate dehydrogenase activity. Concentrations of plasminogen activator (tPA) and plasminogen activator inhibitor 1 (PAI-1) as measures of the fibrinolytic activity of mesothelial cells. Both activated carbon and MMC-CH caused a significant increase of adhesion formation in rats. Activated carbon also reduced the fibrinolytic activity of mesothelial cells, and mitomycin C caused concentration-dependent cytotoxicity in vitro. Activated carbon combined with high concentrations of mitomycin C may cause intraperitoneal infective complications by increasing the rate of adhesion formation and reducing the fibrinolytic activity of mesothelial cells. We recommend a new absorbable carrier for intraperitoneal chemotherapy." @default.
- W2162238216 created "2016-06-24" @default.
- W2162238216 creator A5005788070 @default.
- W2162238216 date "2000-08-08" @default.
- W2162238216 modified "2023-10-14" @default.
- W2162238216 title "Effects of Intraperitoneal Mitomycin C Adsorbed on Activated Carbon on Adhesion Formation and Mesothelial Cells In Vitro" @default.
- W2162238216 cites W1984579087 @default.
- W2162238216 cites W2009444241 @default.
- W2162238216 cites W2010143128 @default.
- W2162238216 cites W2023154641 @default.
- W2162238216 cites W2039211516 @default.
- W2162238216 cites W2064936790 @default.
- W2162238216 cites W2086965262 @default.
- W2162238216 cites W2091801981 @default.
- W2162238216 cites W2092835614 @default.
- W2162238216 cites W2093741658 @default.
- W2162238216 cites W2114335746 @default.
- W2162238216 cites W2187098903 @default.
- W2162238216 cites W2416350203 @default.
- W2162238216 cites W62928356 @default.
- W2162238216 doi "https://doi.org/10.1080/110241500750008664" @default.
- W2162238216 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10965838" @default.
- W2162238216 hasPublicationYear "2000" @default.
- W2162238216 type Work @default.
- W2162238216 sameAs 2162238216 @default.
- W2162238216 citedByCount "5" @default.
- W2162238216 countsByYear W21622382162013 @default.
- W2162238216 crossrefType "journal-article" @default.
- W2162238216 hasAuthorship W2162238216A5005788070 @default.
- W2162238216 hasConcept C126322002 @default.
- W2162238216 hasConcept C141071460 @default.
- W2162238216 hasConcept C142724271 @default.
- W2162238216 hasConcept C178790620 @default.
- W2162238216 hasConcept C185592680 @default.
- W2162238216 hasConcept C202751555 @default.
- W2162238216 hasConcept C2779338040 @default.
- W2162238216 hasConcept C2779679481 @default.
- W2162238216 hasConcept C2779747549 @default.
- W2162238216 hasConcept C2780159080 @default.
- W2162238216 hasConcept C2909640154 @default.
- W2162238216 hasConcept C55493867 @default.
- W2162238216 hasConcept C71924100 @default.
- W2162238216 hasConcept C84416704 @default.
- W2162238216 hasConcept C85789140 @default.
- W2162238216 hasConcept C98274493 @default.
- W2162238216 hasConceptScore W2162238216C126322002 @default.
- W2162238216 hasConceptScore W2162238216C141071460 @default.
- W2162238216 hasConceptScore W2162238216C142724271 @default.
- W2162238216 hasConceptScore W2162238216C178790620 @default.
- W2162238216 hasConceptScore W2162238216C185592680 @default.
- W2162238216 hasConceptScore W2162238216C202751555 @default.
- W2162238216 hasConceptScore W2162238216C2779338040 @default.
- W2162238216 hasConceptScore W2162238216C2779679481 @default.
- W2162238216 hasConceptScore W2162238216C2779747549 @default.
- W2162238216 hasConceptScore W2162238216C2780159080 @default.
- W2162238216 hasConceptScore W2162238216C2909640154 @default.
- W2162238216 hasConceptScore W2162238216C55493867 @default.
- W2162238216 hasConceptScore W2162238216C71924100 @default.
- W2162238216 hasConceptScore W2162238216C84416704 @default.
- W2162238216 hasConceptScore W2162238216C85789140 @default.
- W2162238216 hasConceptScore W2162238216C98274493 @default.
- W2162238216 hasIssue "7" @default.
- W2162238216 hasLocation W21622382161 @default.
- W2162238216 hasLocation W21622382162 @default.
- W2162238216 hasOpenAccess W2162238216 @default.
- W2162238216 hasPrimaryLocation W21622382161 @default.
- W2162238216 hasRelatedWork W2032966146 @default.
- W2162238216 hasRelatedWork W2036019161 @default.
- W2162238216 hasRelatedWork W2038183635 @default.
- W2162238216 hasRelatedWork W2065904376 @default.
- W2162238216 hasRelatedWork W2068876691 @default.
- W2162238216 hasRelatedWork W2162238216 @default.
- W2162238216 hasRelatedWork W2170770553 @default.
- W2162238216 hasRelatedWork W2388109082 @default.
- W2162238216 hasRelatedWork W2781248984 @default.
- W2162238216 hasRelatedWork W4321253642 @default.
- W2162238216 hasVolume "166" @default.
- W2162238216 isParatext "false" @default.
- W2162238216 isRetracted "false" @default.
- W2162238216 magId "2162238216" @default.
- W2162238216 workType "article" @default.