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• W2162265847 abstract "The C-terminal coding region of the gene (denoted csh A) encoding a high-molecular-mass (290 kDa) cell-surface polypeptide in the oral bacterium Streptococcus gordonii was cloned and sequenced. Insertion of ermAM into the S. gordonii chromosome at the 3′ end of the coding region of cshA led to the production of isogenic mutants that secreted a truncated form (260 kDa) of the CshA polypeptide into the growth medium. Mutants had reduced cell-surface hydrophobicity and were impaired in their ability to coaggregate with oral actinomyces. The results identify a carboxyl terminus-anchored cell-surface protein determinant of hydrophobicity and coaggregation in S. gordonii" @default.
• W2162265847 created "2016-06-24" @default.
• W2162265847 creator A5038488437 @default.
• W2162265847 creator A5049815660 @default.
• W2162265847 date "1992-10-01" @default.
• W2162265847 modified "2023-09-23" @default.
• W2162265847 title "Gene disruption identifies a 290 kDa cell-surface polypeptide conferring hydrophobicity and coaggregation properties in Streptococcus gordonii" @default.
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• W2162265847 doi "https://doi.org/10.1111/j.1365-2958.1992.tb01753.x" @default.
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