Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162269749> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2162269749 endingPage "148" @default.
- W2162269749 startingPage "143" @default.
- W2162269749 abstract "We studied the effect of N-(6-aminohexyl)-5-chloro-1-napthalenesulfonamide (W-7) on ultraviolet radiation (UVR)-induced melanogenesis (tanning) in Skh:HR2 pigmented hairless mice. Topically pretreated mice were exposed to subminimal edematogenic as well as edematogenic UVR doses to establish whether W-7-UVR-induced edema prophylaxis allows increased melanogenesis while preventing edema. Ultraviolet light-irradiated vehicle control animals developed visible tans; however, both W-7-treated groups failed to tan. Topical W-7 before UVR exposure inhibited UVR induction of dopa oxidase activity in melanocytes by 49% (P=0.029) and inhibited UVR-induced deposition of melanin in the epidermis by 88% (P=0.006). Topical W-7 blocked 23% of the UVR but this blockage could not account for the inhibition of dopa oxidase and melanization. We conclude that, in addition to preventing edema, W-7 inhibits UVR-induced melanogenesis, possibly by affecting Ca2+-calmodulin and/or protein kinase C-dependent processes." @default.
- W2162269749 created "2016-06-24" @default.
- W2162269749 creator A5013391866 @default.
- W2162269749 creator A5042479458 @default.
- W2162269749 creator A5055181183 @default.
- W2162269749 date "1995-08-01" @default.
- W2162269749 modified "2023-09-25" @default.
- W2162269749 title "Topical W-7 inhibits ultraviolet radiation-induced melanogenesis in Skh:HR2 pigmented hairless mice" @default.
- W2162269749 cites W1978502742 @default.
- W2162269749 cites W1981282395 @default.
- W2162269749 cites W1983266019 @default.
- W2162269749 cites W2009023255 @default.
- W2162269749 cites W2013076394 @default.
- W2162269749 cites W2015427668 @default.
- W2162269749 cites W2034025188 @default.
- W2162269749 cites W2044327206 @default.
- W2162269749 cites W2053977768 @default.
- W2162269749 cites W2057994554 @default.
- W2162269749 cites W2069109567 @default.
- W2162269749 cites W2072855776 @default.
- W2162269749 cites W2073724284 @default.
- W2162269749 cites W2075896173 @default.
- W2162269749 cites W2080614550 @default.
- W2162269749 cites W2087802102 @default.
- W2162269749 cites W2094473164 @default.
- W2162269749 cites W2107028037 @default.
- W2162269749 cites W26501635 @default.
- W2162269749 doi "https://doi.org/10.1111/j.1600-0781.1995.tb00156.x" @default.
- W2162269749 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8850246" @default.
- W2162269749 hasPublicationYear "1995" @default.
- W2162269749 type Work @default.
- W2162269749 sameAs 2162269749 @default.
- W2162269749 citedByCount "3" @default.
- W2162269749 crossrefType "journal-article" @default.
- W2162269749 hasAuthorship W2162269749A5013391866 @default.
- W2162269749 hasAuthorship W2162269749A5042479458 @default.
- W2162269749 hasAuthorship W2162269749A5055181183 @default.
- W2162269749 hasConcept C105702510 @default.
- W2162269749 hasConcept C107538193 @default.
- W2162269749 hasConcept C126322002 @default.
- W2162269749 hasConcept C153911025 @default.
- W2162269749 hasConcept C16005928 @default.
- W2162269749 hasConcept C177322064 @default.
- W2162269749 hasConcept C185592680 @default.
- W2162269749 hasConcept C2776458125 @default.
- W2162269749 hasConcept C2779156968 @default.
- W2162269749 hasConcept C2780886150 @default.
- W2162269749 hasConcept C2987742019 @default.
- W2162269749 hasConcept C3017420807 @default.
- W2162269749 hasConcept C55493867 @default.
- W2162269749 hasConcept C71924100 @default.
- W2162269749 hasConcept C86803240 @default.
- W2162269749 hasConcept C98274493 @default.
- W2162269749 hasConceptScore W2162269749C105702510 @default.
- W2162269749 hasConceptScore W2162269749C107538193 @default.
- W2162269749 hasConceptScore W2162269749C126322002 @default.
- W2162269749 hasConceptScore W2162269749C153911025 @default.
- W2162269749 hasConceptScore W2162269749C16005928 @default.
- W2162269749 hasConceptScore W2162269749C177322064 @default.
- W2162269749 hasConceptScore W2162269749C185592680 @default.
- W2162269749 hasConceptScore W2162269749C2776458125 @default.
- W2162269749 hasConceptScore W2162269749C2779156968 @default.
- W2162269749 hasConceptScore W2162269749C2780886150 @default.
- W2162269749 hasConceptScore W2162269749C2987742019 @default.
- W2162269749 hasConceptScore W2162269749C3017420807 @default.
- W2162269749 hasConceptScore W2162269749C55493867 @default.
- W2162269749 hasConceptScore W2162269749C71924100 @default.
- W2162269749 hasConceptScore W2162269749C86803240 @default.
- W2162269749 hasConceptScore W2162269749C98274493 @default.
- W2162269749 hasIssue "4" @default.
- W2162269749 hasLocation W21622697491 @default.
- W2162269749 hasLocation W21622697492 @default.
- W2162269749 hasOpenAccess W2162269749 @default.
- W2162269749 hasPrimaryLocation W21622697491 @default.
- W2162269749 hasRelatedWork W1998469468 @default.
- W2162269749 hasRelatedWork W2006961921 @default.
- W2162269749 hasRelatedWork W2015427668 @default.
- W2162269749 hasRelatedWork W2049293980 @default.
- W2162269749 hasRelatedWork W2068944232 @default.
- W2162269749 hasRelatedWork W2291943127 @default.
- W2162269749 hasRelatedWork W2331268883 @default.
- W2162269749 hasRelatedWork W2935337431 @default.
- W2162269749 hasRelatedWork W3162427139 @default.
- W2162269749 hasRelatedWork W3209656339 @default.
- W2162269749 hasVolume "11" @default.
- W2162269749 isParatext "false" @default.
- W2162269749 isRetracted "false" @default.
- W2162269749 magId "2162269749" @default.
- W2162269749 workType "article" @default.