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• W2162270434 abstract "The aptitude of a cell to adhere, migrate, and differentiate on a compact substrate or scaffold is important in the field of tissue engineering and biomaterials. It is well known that cell behavior can be controlled and guided through the change in micro- and nano-scale topographic features. In this work, we intend to demonstrate that special topographic features that control wettability may also have an important role in the biological performance of biodegradable substrates. Poly(L-lactic acid) surfaces with superhydrophobic characteristics were produced, based on the so-called Lotus effect, exhibiting dual micro- and nano-scale roughness. The water contact angle could be higher than 150 degrees and a value of that order could be kept even upon immersion in a simulated body fluid solution for more than 20 days. Such water repellent surfaces were found to prevent adhesion and proliferation of bone marrow derived cells previously isolated from the femurs of 6-week-old male Wistar rats, when compared with smoother surfaces prepared by simple solvent casting. Such results demonstrate that these superhydrophobic surfaces may be used to control cell behavior onto biodegradable substrates." @default.
• W2162270434 created "2016-06-24" @default.
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• W2162270434 date "2008-11-04" @default.
• W2162270434 modified "2023-10-10" @default.
• W2162270434 title "Bioinspired superhydrophobic poly(L-lactic acid) surfaces control bone marrow derived cells adhesion and proliferation" @default.
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• W2162270434 doi "https://doi.org/10.1002/jbm.a.32210" @default.
• W2162270434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18985759" @default.
• W2162270434 hasPublicationYear "2008" @default.
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