FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162273208> ?p ?o ?g. }

• W2162273208 endingPage "600" @default.
• W2162273208 startingPage "597" @default.
• W2162273208 abstract "Animal models suggest that androgen receptor gene polymorphisms might affect disease predisposition in human immune-mediated diabetes. The aim of this study was to investigate the effect of the human androgen receptor gene exon 1 CAG repeat polymorphisms on type 1 diabetes (T1D) susceptibility.A combined strategy of case-control and family-based approaches was used. Affected sibling pair families (n=120), nuclear families (n=645) and cohorts of sporadic cases (n=208) and controls (n=1381) were genotyped for androgen receptor gene exon 1 CAG repeat polymorphism. An automated fluorescence-based DNA fragment-sizing method was used.The distribution of CAG repeat alleles did not differ significantly between patients and controls. However, short repeat alleles (7-14) were more prevalent among cases in girls compared with controls (8.77% vs 5.91%; P=0.03). Long repeat alleles (19-28) were less frequent among HLA DR3-positive diseased boys than in DR3-positive control boys (32.6% vs 40.6%; P=0.011). The differences were not significant after adjustment for multiple comparisons. Transmission of CAG repeat alleles was not different from expected in the total material. However, transmissions to girls deviated from the expected value significantly (extended transmission disequilibrium test (ETDT) 37.82; P=0.0016). A decreased transmission of the alleles with 13, 20 and 26 repeats to girls was observed (T%0, P=0.046; T%25.5, P=0.0003, T%0, P=0.025).The results do not support a common role for the androgen receptor gene exon 1 CAG repeat in T1D susceptibility; however, an effect of a disease variant in linkage disequilibrium could be detected." @default.
• W2162273208 created "2016-06-24" @default.
• W2162273208 creator A5000141478 @default.
• W2162273208 creator A5000991422 @default.
• W2162273208 creator A5001640598 @default.
• W2162273208 creator A5048692933 @default.
• W2162273208 creator A5062161012 @default.
• W2162273208 creator A5066618511 @default.
• W2162273208 creator A5088970962 @default.
• W2162273208 date "2003-12-01" @default.
• W2162273208 modified "2023-10-17" @default.
• W2162273208 title "Androgen receptor gene exon 1 CAG repeat polymorphism in Finnish patients with childhood-onset type 1 diabetes" @default.
• W2162273208 cites W1487018400 @default.
• W2162273208 cites W1489135971 @default.
• W2162273208 cites W1966489527 @default.
• W2162273208 cites W1990973025 @default.
• W2162273208 cites W1998476721 @default.
• W2162273208 cites W2006203084 @default.
• W2162273208 cites W2029180509 @default.
• W2162273208 cites W2038277515 @default.
• W2162273208 cites W2046118584 @default.
• W2162273208 cites W2050602600 @default.
• W2162273208 cites W2052870879 @default.
• W2162273208 cites W2055388500 @default.
• W2162273208 cites W2058535370 @default.
• W2162273208 cites W2074891952 @default.
• W2162273208 cites W2077335838 @default.
• W2162273208 cites W2101065984 @default.
• W2162273208 cites W2109332045 @default.
• W2162273208 cites W2113333419 @default.
• W2162273208 cites W2113586939 @default.
• W2162273208 cites W2118094114 @default.
• W2162273208 cites W2124759347 @default.
• W2162273208 cites W2149169654 @default.
• W2162273208 cites W2164392517 @default.
• W2162273208 cites W2171578818 @default.
• W2162273208 cites W2403319411 @default.
• W2162273208 cites W2431066538 @default.
• W2162273208 cites W3148262834 @default.
• W2162273208 cites W137161424 @default.
• W2162273208 doi "https://doi.org/10.1530/eje.0.1490597" @default.
• W2162273208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14641003" @default.
• W2162273208 hasPublicationYear "2003" @default.
• W2162273208 type Work @default.
• W2162273208 sameAs 2162273208 @default.
• W2162273208 citedByCount "4" @default.
• W2162273208 crossrefType "journal-article" @default.
• W2162273208 hasAuthorship W2162273208A5000141478 @default.
• W2162273208 hasAuthorship W2162273208A5000991422 @default.
• W2162273208 hasAuthorship W2162273208A5001640598 @default.
• W2162273208 hasAuthorship W2162273208A5048692933 @default.
• W2162273208 hasAuthorship W2162273208A5062161012 @default.
• W2162273208 hasAuthorship W2162273208A5066618511 @default.
• W2162273208 hasAuthorship W2162273208A5088970962 @default.
• W2162273208 hasBestOaLocation W21622732081 @default.
• W2162273208 hasConcept C104317684 @default.
• W2162273208 hasConcept C121608353 @default.
• W2162273208 hasConcept C126322002 @default.
• W2162273208 hasConcept C134018914 @default.
• W2162273208 hasConcept C180754005 @default.
• W2162273208 hasConcept C2777911890 @default.
• W2162273208 hasConcept C2780192828 @default.
• W2162273208 hasConcept C36823959 @default.
• W2162273208 hasConcept C54355233 @default.
• W2162273208 hasConcept C61367390 @default.
• W2162273208 hasConcept C71315377 @default.
• W2162273208 hasConcept C71924100 @default.
• W2162273208 hasConcept C86803240 @default.
• W2162273208 hasConceptScore W2162273208C104317684 @default.
• W2162273208 hasConceptScore W2162273208C121608353 @default.
• W2162273208 hasConceptScore W2162273208C126322002 @default.
• W2162273208 hasConceptScore W2162273208C134018914 @default.
• W2162273208 hasConceptScore W2162273208C180754005 @default.
• W2162273208 hasConceptScore W2162273208C2777911890 @default.
• W2162273208 hasConceptScore W2162273208C2780192828 @default.
• W2162273208 hasConceptScore W2162273208C36823959 @default.
• W2162273208 hasConceptScore W2162273208C54355233 @default.
• W2162273208 hasConceptScore W2162273208C61367390 @default.
• W2162273208 hasConceptScore W2162273208C71315377 @default.
• W2162273208 hasConceptScore W2162273208C71924100 @default.
• W2162273208 hasConceptScore W2162273208C86803240 @default.
• W2162273208 hasLocation W21622732081 @default.
• W2162273208 hasLocation W21622732082 @default.
• W2162273208 hasOpenAccess W2162273208 @default.
• W2162273208 hasPrimaryLocation W21622732081 @default.
• W2162273208 hasRelatedWork W2004261902 @default.
• W2162273208 hasRelatedWork W2058317585 @default.
• W2162273208 hasRelatedWork W2068395526 @default.
• W2162273208 hasRelatedWork W2072661483 @default.
• W2162273208 hasRelatedWork W2075574887 @default.
• W2162273208 hasRelatedWork W2103250319 @default.
• W2162273208 hasRelatedWork W2121679333 @default.
• W2162273208 hasRelatedWork W2136266902 @default.
• W2162273208 hasRelatedWork W2171723716 @default.
• W2162273208 hasRelatedWork W2343995045 @default.
• W2162273208 isParatext "false" @default.
• W2162273208 isRetracted "false" @default.
• W2162273208 magId "2162273208" @default.

• next