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• W2162284009 endingPage "422" @default.
• W2162284009 startingPage "409" @default.
• W2162284009 abstract "Norepinephrine (NE) was released from perfused spleens either by nerve stimulation or injection of potassium in phenoxybenzamine-treated and normal cats. Krebs-bicarbonate solution was perfused at a rate of about 7 ml/min at 35°C. Perfusion of the phenoxybenzamine-treated spleens with 2.5 mM Mn⁺⁺ Krebs9 solution reduced the NE outputs to low levels. Perfusion of the normal spleens, pre-exposed to H³-NE infusion, with 0.8, 2.5 or 5 mM Mn⁺⁺ Krebs9 solution also significantly reduced the net increases in radioactivity, H³-NE and NE by nerve stimulation. Increasing the Ca⁺⁺ concentration to 10 mM did not significantly alter the inhibitory effect of Mn⁺⁺. Mn⁺⁺ also blocked the spontaneous release of radioactivity from spleen. It is concluded that Mn⁺⁺ acts as a potent inhibitor of NE release and blocks both the nerve-induced and spontaneous release of NE." @default.
• W2162284009 created "2016-06-24" @default.
• W2162284009 creator A5012686323 @default.
• W2162284009 creator A5067766130 @default.
• W2162284009 creator A5070150431 @default.
• W2162284009 date "2006-08-01" @default.
• W2162284009 modified "2023-10-18" @default.
• W2162284009 title "Thoracoscopy: general overview and place in the diagnosis and management of pleural effusion" @default.
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• W2162284009 doi "https://doi.org/10.1183/09031936.06.00013706" @default.
• W2162284009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16880371" @default.

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