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• W2162285997 abstract "The MRI T 1 proton relaxation values were assessed in 14 patients with bipolar affective disorder and 10 with a unipolar disorder and a matched normal control group. The T 1 values in the frontal white matter of patients significantly exceeded those of the controls. This difference was accounted for by an increase in T 1 values in the frontal white matter of unipolar patients: the values for bipolar patients alone did not differ from those for controls. These preliminary findings support a hypothesis of frontal lobe dysfunction mediating pathological changes in mood." @default.
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• W2162285997 date "1990-07-01" @default.
• W2162285997 modified "2023-09-24" @default.
• W2162285997 title "Altered Magnetic Resonance White-Matter <i>T</i>₁ Values in Patients with Affective Disorder" @default.
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• W2162285997 doi "https://doi.org/10.1192/bjp.157.1.107" @default.
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