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• W2162288669 abstract "Liver biopsy continues to play a critical role in the evaluation and management of patients with liver disease. Although history, physical examination, and serological markers often obviate the need for a diagnostic liver biopsy, it is still considered the criterion standard, especially when the etiology of liver disease remains obscure. Even with a thorough history and laboratory workup, significant fibrosis and/or cirrhosis can be missed in as many as 32% of patients without a liver biopsy. 1 Skelly M.M. James P.D. Ryder S.D. Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology. J Hepatol. 2001; 35: 195-199 Abstract Full Text Full Text PDF PubMed Scopus (264) Google Scholar In fact, results of a liver biopsy have been shown to alter diagnosis in as many as 14% of patients with chronically elevated liver enzymes and significantly affect patient management in as many as 18% of such patients. 1 Skelly M.M. James P.D. Ryder S.D. Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology. J Hepatol. 2001; 35: 195-199 Abstract Full Text Full Text PDF PubMed Scopus (264) Google Scholar , 2 Sorbi D. McGill D.B. Thistle T.L. et al. An assessment of the role of liver biopsies in asymptomatic patients with chronic liver test abnormalities. Am J Gastroenterol. 2000; 95: 3206-3210 Crossref PubMed Google Scholar Moreover, current noninvasive imaging and serological markers of hepatic fibrosis remain investigational and have not been shown to be as accurate as liver biopsy." @default.
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• W2162288669 date "2014-01-01" @default.
• W2162288669 modified "2023-10-03" @default.
• W2162288669 title "Histological adequacy of EUS-guided liver biopsy when using a 19-gauge non–Tru-Cut FNA needle" @default.
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• W2162288669 doi "https://doi.org/10.1016/j.gie.2013.06.031" @default.
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