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- W2162532926 abstract "SUMMARY Parasite burden varies widely between individuals within a population, and can covary with multiple aspects of individual phenotype. Here we investigate the sources of variation in faecal strongyle eggs counts, and its association with body weight and a suite of haematological measures, in a cohort of indigenous zebu calves in Western Kenya, using relatedness matrices reconstructed from single nucleotide polymorphism (SNP) genotypes. Strongyle egg count was heritable ( h 2 = 23·9%, s.e. = 11·8%) and we also found heritability of white blood cell counts (WBC) ( h 2 = 27·6%, s.e. = 10·6%). All the traits investigated showed negative phenotypic covariances with strongyle egg count throughout the first year: high worm counts were associated with low values of WBC, red blood cell count, total serum protein and absolute eosinophil count. Furthermore, calf body weight at 1 week old was a significant predictor of strongyle EPG at 16–51 weeks, with smaller calves having a higher strongyle egg count later in life. Our results indicate a genetic basis to strongyle EPG in this population, and also reveal consistently strong negative associations between strongyle infection and other important aspects of the multivariate phenotype." @default.
- W2162532926 created "2016-06-24" @default.
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- W2162532926 date "2014-09-26" @default.
- W2162532926 modified "2023-09-25" @default.
- W2162532926 title "Variation and covariation in strongyle infection in East African shorthorn zebu calves" @default.
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- W2162532926 doi "https://doi.org/10.1017/s0031182014001498" @default.
- W2162532926 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5844460" @default.
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