FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162557589> ?p ?o ?g. }

• W2162557589 endingPage "111" @default.
• W2162557589 startingPage "109" @default.
• W2162557589 abstract "Toll-like receptors (TLRs) are critical components of the pathogen recognition by the host innate immune system. Recently it has been shown that TLR1 is under evolutionary pressure in Europeans. This involves the positive selection of the nonsynonymous TLR1 1805G variant in Europeans, although this is associated with poor TLR1 response and unfavorable prognosis in various infections. In terms of natural selection, differential fertility is another mechanism, independent of infection susceptibility, that may explain the polymorphism pattern observed for TLR1. To test this hypothesis, we assessed the correlation of two TLR1 SNPs (T1805G and G239C) with spontaneous pregnancy loss in a case-control study that included 132 spontaneous pregnancy loss patients and 142 control volunteers. Similar allele frequencies of T1805G were observed between cases and controls, but GG genotype tended to be associated with pregnancy loss (OR 1.91; 95%CI 1.03, 3.53). No differences were observed for the TLR1 G239C SNP. Our findings showed slight differences in the distribution of T1805G variants in women with pregnancy loss, but these were not indicative of a protective effect of the TLR1 1805G allele for this fertility disorder. Although our hypothesis was not proven, potential effects of TLR1 polymorphisms on pregnancy outcome have been suggested, and future studies in larger cohorts are warranted." @default.
• W2162557589 created "2016-06-24" @default.
• W2162557589 creator A5008198824 @default.
• W2162557589 creator A5016959402 @default.
• W2162557589 creator A5017111457 @default.
• W2162557589 creator A5020027280 @default.
• W2162557589 creator A5027955775 @default.
• W2162557589 creator A5044489352 @default.
• W2162557589 creator A5063344258 @default.
• W2162557589 creator A5083629733 @default.
• W2162557589 date "2012-02-01" @default.
• W2162557589 modified "2023-10-17" @default.
• W2162557589 title "TLR1 polymorphisms in Europeans and spontaneous pregnancy loss" @default.
• W2162557589 cites W1482321617 @default.
• W2162557589 cites W1483995798 @default.
• W2162557589 cites W1994942139 @default.
• W2162557589 cites W2006426063 @default.
• W2162557589 cites W2010219741 @default.
• W2162557589 cites W2018883072 @default.
• W2162557589 cites W2058179716 @default.
• W2162557589 cites W2076886077 @default.
• W2162557589 cites W2091229884 @default.
• W2162557589 cites W2097568705 @default.
• W2162557589 cites W2107762058 @default.
• W2162557589 cites W2127533700 @default.
• W2162557589 cites W2138049915 @default.
• W2162557589 cites W2142672161 @default.
• W2162557589 cites W2144136875 @default.
• W2162557589 cites W4211211389 @default.
• W2162557589 doi "https://doi.org/10.1016/j.gene.2011.12.008" @default.
• W2162557589 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22200569" @default.
• W2162557589 hasPublicationYear "2012" @default.
• W2162557589 type Work @default.
• W2162557589 sameAs 2162557589 @default.
• W2162557589 citedByCount "7" @default.
• W2162557589 countsByYear W21625575892012 @default.
• W2162557589 countsByYear W21625575892013 @default.
• W2162557589 countsByYear W21625575892015 @default.
• W2162557589 countsByYear W21625575892018 @default.
• W2162557589 countsByYear W21625575892021 @default.
• W2162557589 countsByYear W21625575892022 @default.
• W2162557589 crossrefType "journal-article" @default.
• W2162557589 hasAuthorship W2162557589A5008198824 @default.
• W2162557589 hasAuthorship W2162557589A5016959402 @default.
• W2162557589 hasAuthorship W2162557589A5017111457 @default.
• W2162557589 hasAuthorship W2162557589A5020027280 @default.
• W2162557589 hasAuthorship W2162557589A5027955775 @default.
• W2162557589 hasAuthorship W2162557589A5044489352 @default.
• W2162557589 hasAuthorship W2162557589A5063344258 @default.
• W2162557589 hasAuthorship W2162557589A5083629733 @default.
• W2162557589 hasConcept C104317684 @default.
• W2162557589 hasConcept C135763542 @default.
• W2162557589 hasConcept C139275648 @default.
• W2162557589 hasConcept C141231307 @default.
• W2162557589 hasConcept C144024400 @default.
• W2162557589 hasConcept C149904235 @default.
• W2162557589 hasConcept C149923435 @default.
• W2162557589 hasConcept C153209595 @default.
• W2162557589 hasConcept C180754005 @default.
• W2162557589 hasConcept C203014093 @default.
• W2162557589 hasConcept C2779234561 @default.
• W2162557589 hasConcept C2908647359 @default.
• W2162557589 hasConcept C37463918 @default.
• W2162557589 hasConcept C518429986 @default.
• W2162557589 hasConcept C54355233 @default.
• W2162557589 hasConcept C86803240 @default.
• W2162557589 hasConceptScore W2162557589C104317684 @default.
• W2162557589 hasConceptScore W2162557589C135763542 @default.
• W2162557589 hasConceptScore W2162557589C139275648 @default.
• W2162557589 hasConceptScore W2162557589C141231307 @default.
• W2162557589 hasConceptScore W2162557589C144024400 @default.
• W2162557589 hasConceptScore W2162557589C149904235 @default.
• W2162557589 hasConceptScore W2162557589C149923435 @default.
• W2162557589 hasConceptScore W2162557589C153209595 @default.
• W2162557589 hasConceptScore W2162557589C180754005 @default.
• W2162557589 hasConceptScore W2162557589C203014093 @default.
• W2162557589 hasConceptScore W2162557589C2779234561 @default.
• W2162557589 hasConceptScore W2162557589C2908647359 @default.
• W2162557589 hasConceptScore W2162557589C37463918 @default.
• W2162557589 hasConceptScore W2162557589C518429986 @default.
• W2162557589 hasConceptScore W2162557589C54355233 @default.
• W2162557589 hasConceptScore W2162557589C86803240 @default.
• W2162557589 hasIssue "1" @default.
• W2162557589 hasLocation W21625575891 @default.
• W2162557589 hasLocation W21625575892 @default.
• W2162557589 hasOpenAccess W2162557589 @default.
• W2162557589 hasPrimaryLocation W21625575891 @default.
• W2162557589 hasRelatedWork W1831672189 @default.
• W2162557589 hasRelatedWork W1977206606 @default.
• W2162557589 hasRelatedWork W1997352593 @default.
• W2162557589 hasRelatedWork W2001142759 @default.
• W2162557589 hasRelatedWork W2013942803 @default.
• W2162557589 hasRelatedWork W2143489661 @default.
• W2162557589 hasRelatedWork W2164855536 @default.
• W2162557589 hasRelatedWork W3016573916 @default.
• W2162557589 hasRelatedWork W3206555169 @default.
• W2162557589 hasRelatedWork W4281711902 @default.
• W2162557589 hasVolume "494" @default.

• next