FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162721071> ?p ?o ?g. }

• W2162721071 endingPage "199" @default.
• W2162721071 startingPage "195" @default.
• W2162721071 abstract "We have studied the effects of pituitary adenylate cyclase-activating polypeptide (PACAP27 and PACAP38) on cyclic AMP formation in chick brain, and the action of melatonin upon the PACAP-evoked effects. PACAP stimulated cyclic AMP production in the hypothalamus>cerebral cortex>pineal gland>optic lobes. In the hypothalamus and cerebral cortex, the rank-order of both PACAP forms and VIP in evoking the cyclic AMP response was: PACAP38≈PACAP27≫VIP, suggesting the presence in the tested tissues of PAC1 receptors. Melatonin suppressed (IC50=19.8 nM) the PACAP27 (0.1 μM)-induced cyclic AMP response in the hypothalamus, but not in the cerebral cortex. Melatonin also suppressed the hypothalamal cyclic AMP synthesis stimulated by forskolin, but not that evoked by histamine or isoprenaline. Our observations show that PACAP is capable of potently stimulating cyclic AMP formation in some regions of the chick brain, and suggest that the hypothalamus may be a site for a functional interaction between PACAP and the pineal hormone melatonin." @default.
• W2162721071 created "2016-06-24" @default.
• W2162721071 creator A5001766678 @default.
• W2162721071 creator A5010148587 @default.
• W2162721071 creator A5069959118 @default.
• W2162721071 date "1999-05-01" @default.
• W2162721071 modified "2023-10-18" @default.
• W2162721071 title "PACAP-induced formation of cyclic AMP in the chicken brain: regional variations and the effect of melatonin" @default.
• W2162721071 cites W1495842154 @default.
• W2162721071 cites W1894685331 @default.
• W2162721071 cites W1918494965 @default.
• W2162721071 cites W1938523556 @default.
• W2162721071 cites W1981423842 @default.
• W2162721071 cites W1987279834 @default.
• W2162721071 cites W1987346819 @default.
• W2162721071 cites W1993137551 @default.
• W2162721071 cites W1997617757 @default.
• W2162721071 cites W1999969694 @default.
• W2162721071 cites W2003765070 @default.
• W2162721071 cites W2008032811 @default.
• W2162721071 cites W2011378156 @default.
• W2162721071 cites W2014585127 @default.
• W2162721071 cites W2014676456 @default.
• W2162721071 cites W2022841539 @default.
• W2162721071 cites W2033650768 @default.
• W2162721071 cites W2036120795 @default.
• W2162721071 cites W2037331744 @default.
• W2162721071 cites W2040554445 @default.
• W2162721071 cites W2042732012 @default.
• W2162721071 cites W2049059486 @default.
• W2162721071 cites W2058104052 @default.
• W2162721071 cites W2069778823 @default.
• W2162721071 cites W2087708630 @default.
• W2162721071 cites W2090966569 @default.
• W2162721071 cites W2114384467 @default.
• W2162721071 cites W2127339663 @default.
• W2162721071 cites W2136350449 @default.
• W2162721071 cites W2164074475 @default.
• W2162721071 cites W2169503005 @default.
• W2162721071 cites W2395559202 @default.
• W2162721071 cites W996315821 @default.
• W2162721071 doi "https://doi.org/10.1016/s0006-8993(99)01367-0" @default.
• W2162721071 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10350575" @default.
• W2162721071 hasPublicationYear "1999" @default.
• W2162721071 type Work @default.
• W2162721071 sameAs 2162721071 @default.
• W2162721071 citedByCount "23" @default.
• W2162721071 crossrefType "journal-article" @default.
• W2162721071 hasAuthorship W2162721071A5001766678 @default.
• W2162721071 hasAuthorship W2162721071A5010148587 @default.
• W2162721071 hasAuthorship W2162721071A5069959118 @default.
• W2162721071 hasConcept C118303440 @default.
• W2162721071 hasConcept C126322002 @default.
• W2162721071 hasConcept C134018914 @default.
• W2162721071 hasConcept C170493617 @default.
• W2162721071 hasConcept C180526460 @default.
• W2162721071 hasConcept C185592680 @default.
• W2162721071 hasConcept C2777003273 @default.
• W2162721071 hasConcept C2778182776 @default.
• W2162721071 hasConcept C2779276759 @default.
• W2162721071 hasConcept C2780059843 @default.
• W2162721071 hasConcept C2780069284 @default.
• W2162721071 hasConcept C2781041448 @default.
• W2162721071 hasConcept C71924100 @default.
• W2162721071 hasConcept C8330315 @default.
• W2162721071 hasConcept C86803240 @default.
• W2162721071 hasConceptScore W2162721071C118303440 @default.
• W2162721071 hasConceptScore W2162721071C126322002 @default.
• W2162721071 hasConceptScore W2162721071C134018914 @default.
• W2162721071 hasConceptScore W2162721071C170493617 @default.
• W2162721071 hasConceptScore W2162721071C180526460 @default.
• W2162721071 hasConceptScore W2162721071C185592680 @default.
• W2162721071 hasConceptScore W2162721071C2777003273 @default.
• W2162721071 hasConceptScore W2162721071C2778182776 @default.
• W2162721071 hasConceptScore W2162721071C2779276759 @default.
• W2162721071 hasConceptScore W2162721071C2780059843 @default.
• W2162721071 hasConceptScore W2162721071C2780069284 @default.
• W2162721071 hasConceptScore W2162721071C2781041448 @default.
• W2162721071 hasConceptScore W2162721071C71924100 @default.
• W2162721071 hasConceptScore W2162721071C8330315 @default.
• W2162721071 hasConceptScore W2162721071C86803240 @default.
• W2162721071 hasIssue "1" @default.
• W2162721071 hasLocation W21627210711 @default.
• W2162721071 hasLocation W21627210712 @default.
• W2162721071 hasOpenAccess W2162721071 @default.
• W2162721071 hasPrimaryLocation W21627210711 @default.
• W2162721071 hasRelatedWork W2000223190 @default.
• W2162721071 hasRelatedWork W2016899150 @default.
• W2162721071 hasRelatedWork W2017830665 @default.
• W2162721071 hasRelatedWork W2034431520 @default.
• W2162721071 hasRelatedWork W2056306087 @default.
• W2162721071 hasRelatedWork W2062633278 @default.
• W2162721071 hasRelatedWork W2084775804 @default.
• W2162721071 hasRelatedWork W2162721071 @default.
• W2162721071 hasRelatedWork W2398181117 @default.
• W2162721071 hasRelatedWork W2474742919 @default.
• W2162721071 hasVolume "830" @default.
• W2162721071 isParatext "false" @default.

• next