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- W2162765431 abstract "Motor learning in the vestibulo-ocular reflex (VOR) and eyeblink conditioning use similar neural circuitry, and they may use similar cellular plasticity mechanisms. Classically conditioned eyeblink responses undergo extinction after prolonged exposure to the conditioned stimulus in the absence of the unconditioned stimulus. We investigated the possibility that a process similar to extinction may reverse learned changes in the VOR. We induced a learned alteration of the VOR response in rhesus monkeys using magnifying or miniaturizing goggles, which caused head movements to be accompanied by visual image motion. After learning, head movements in the absence of visual stimulation caused a loss of the learned eye movement response. When the learned gain was low, this reversal of learning occurred only when head movements were delivered, and not when the head was held stationary in the absence of visual input, suggesting that this reversal is mediated by an active, extinction-like process." @default.
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- W2162765431 date "2004-09-01" @default.
- W2162765431 modified "2023-09-28" @default.
- W2162765431 title "Reversal of Motor Learning in the Vestibulo-Ocular Reflex in the Absence of Visual Input" @default.
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- W2162765431 doi "https://doi.org/10.1101/lm.82304" @default.
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