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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162803937> ?p ?o ?g. }

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• W2162803937 abstract "The jasmonates, cis-jasmone (CJ) and methyl jasmonate (MJ), were investigated for their effects against NSCLC cell lines A549 and H520. CJ or MJ inhibited the proliferation of both cell lines in a dose-dependent manner as well as induced cell cycle arrest in the G2/M phase. Apoptosis was observed following treatment with CJ or MJ as indicated by Hoechst staining and confirmed by dual annexin V-fluorescein isothiocyanate (FITC)/prodium iodide (PI) and DAPI (4',6-diamidine-2'-phenylindole dihydrochloride) staining. p38 and extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation was observed with increased expression of bax, p21, and caspase-3 activity. These observations indicate that jasmonates may have a therapeutic value in the treatment of lung cancer." @default.
• W2162803937 created "2016-06-24" @default.
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• W2162803937 date "2006-01-01" @default.
• W2162803937 modified "2023-09-27" @default.
• W2162803937 title "JASMONATES INDUCE APOPTOSIS AND CELL CYCLE ARREST IN NON-SMALL CELL LUNG CANCER LINES" @default.
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• W2162803937 doi "https://doi.org/10.1080/01902140601059604" @default.
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