FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162817561> ?p ?o ?g. }

• W2162817561 endingPage "1355" @default.
• W2162817561 startingPage "1349" @default.
• W2162817561 abstract "The objective of this clinical study was to test if blood from osteoarthritis (OA) patients (n = 105) could be processed by a device system to form an autologous protein solution (APS) with preferentially increased concentrations of anti-inflammatory cytokines compared to inflammatory cytokines. To address this objective, APS was prepared from patients exhibiting radiographic evidence of knee OA. Patient metrics were collected including: demographic information, medical history, medication records, and Knee Injury and Osteoarthritis Outcome Score (KOOS) surveys. Cytokine and growth factor concentrations in whole blood and APS were measured using enzyme-linked immunosorbent assays. Statistical analyses were used to identify relationships between OA patient metrics and cytokines. The results of this study indicated that anti-inflammatory cytokines were preferentially increased compared to inflammatory cytokines in APS from 98% of OA patients. APS contained high concentrations of anti-inflammatory proteins including 39,000 ± 20,000 pg/ml IL-1ra, 21,000 ± 5,000 pg/ml sIL-1RII, 2,100 ± 570 pg/ml sTNF-RI, and 4,200 ± 1,500 pg/ml sTNF-RII. Analysis of the 82 patient metrics indicated that no single patient metric was strongly correlated (R2 > 0.7) with the key cytokine concentrations in APS. Therefore, APS can be prepared from a broad range of OA patients. © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:1349–1355, 2014." @default.
• W2162817561 created "2016-06-24" @default.
• W2162817561 creator A5018971052 @default.
• W2162817561 creator A5025013676 @default.
• W2162817561 creator A5028666606 @default.
• W2162817561 creator A5038059460 @default.
• W2162817561 creator A5041958627 @default.
• W2162817561 creator A5052017291 @default.
• W2162817561 creator A5073302842 @default.
• W2162817561 creator A5078423795 @default.
• W2162817561 creator A5087987774 @default.
• W2162817561 date "2014-07-01" @default.
• W2162817561 modified "2023-10-17" @default.
• W2162817561 title "Autologous protein solution prepared from the blood of osteoarthritic patients contains an enhanced profile of anti-inflammatory cytokines and anabolic growth factors" @default.
• W2162817561 cites W1548159556 @default.
• W2162817561 cites W1594588076 @default.
• W2162817561 cites W1716794597 @default.
• W2162817561 cites W1910189841 @default.
• W2162817561 cites W1954024552 @default.
• W2162817561 cites W1964807372 @default.
• W2162817561 cites W1970607681 @default.
• W2162817561 cites W1985425684 @default.
• W2162817561 cites W1998361394 @default.
• W2162817561 cites W2002665105 @default.
• W2162817561 cites W2016724821 @default.
• W2162817561 cites W2023731005 @default.
• W2162817561 cites W2027672301 @default.
• W2162817561 cites W2039808705 @default.
• W2162817561 cites W2041413607 @default.
• W2162817561 cites W2046296524 @default.
• W2162817561 cites W2055019305 @default.
• W2162817561 cites W2060189174 @default.
• W2162817561 cites W2067048458 @default.
• W2162817561 cites W2073111239 @default.
• W2162817561 cites W2077531877 @default.
• W2162817561 cites W2092156139 @default.
• W2162817561 cites W2092882081 @default.
• W2162817561 cites W2098153182 @default.
• W2162817561 cites W2106764617 @default.
• W2162817561 cites W2111780634 @default.
• W2162817561 cites W2139523975 @default.
• W2162817561 cites W2141157018 @default.
• W2162817561 cites W2141380869 @default.
• W2162817561 cites W2148080767 @default.
• W2162817561 cites W2153560938 @default.
• W2162817561 doi "https://doi.org/10.1002/jor.22671" @default.
• W2162817561 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4134723" @default.
• W2162817561 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24981198" @default.
• W2162817561 hasPublicationYear "2014" @default.
• W2162817561 type Work @default.
• W2162817561 sameAs 2162817561 @default.
• W2162817561 citedByCount "49" @default.
• W2162817561 countsByYear W21628175612015 @default.
• W2162817561 countsByYear W21628175612016 @default.
• W2162817561 countsByYear W21628175612017 @default.
• W2162817561 countsByYear W21628175612018 @default.
• W2162817561 countsByYear W21628175612019 @default.
• W2162817561 countsByYear W21628175612020 @default.
• W2162817561 countsByYear W21628175612021 @default.
• W2162817561 countsByYear W21628175612022 @default.
• W2162817561 countsByYear W21628175612023 @default.
• W2162817561 crossrefType "journal-article" @default.
• W2162817561 hasAuthorship W2162817561A5018971052 @default.
• W2162817561 hasAuthorship W2162817561A5025013676 @default.
• W2162817561 hasAuthorship W2162817561A5028666606 @default.
• W2162817561 hasAuthorship W2162817561A5038059460 @default.
• W2162817561 hasAuthorship W2162817561A5041958627 @default.
• W2162817561 hasAuthorship W2162817561A5052017291 @default.
• W2162817561 hasAuthorship W2162817561A5073302842 @default.
• W2162817561 hasAuthorship W2162817561A5078423795 @default.
• W2162817561 hasAuthorship W2162817561A5087987774 @default.
• W2162817561 hasBestOaLocation W21628175611 @default.
• W2162817561 hasConcept C1008401 @default.
• W2162817561 hasConcept C126322002 @default.
• W2162817561 hasConcept C142724271 @default.
• W2162817561 hasConcept C164027704 @default.
• W2162817561 hasConcept C204787440 @default.
• W2162817561 hasConcept C2776164576 @default.
• W2162817561 hasConcept C2776914184 @default.
• W2162817561 hasConcept C2778690821 @default.
• W2162817561 hasConcept C71924100 @default.
• W2162817561 hasConceptScore W2162817561C1008401 @default.
• W2162817561 hasConceptScore W2162817561C126322002 @default.
• W2162817561 hasConceptScore W2162817561C142724271 @default.
• W2162817561 hasConceptScore W2162817561C164027704 @default.
• W2162817561 hasConceptScore W2162817561C204787440 @default.
• W2162817561 hasConceptScore W2162817561C2776164576 @default.
• W2162817561 hasConceptScore W2162817561C2776914184 @default.
• W2162817561 hasConceptScore W2162817561C2778690821 @default.
• W2162817561 hasConceptScore W2162817561C71924100 @default.
• W2162817561 hasFunder F4320310531 @default.
• W2162817561 hasIssue "10" @default.
• W2162817561 hasLocation W21628175611 @default.
• W2162817561 hasLocation W21628175612 @default.
• W2162817561 hasLocation W21628175613 @default.
• W2162817561 hasLocation W21628175614 @default.
• W2162817561 hasOpenAccess W2162817561 @default.
• W2162817561 hasPrimaryLocation W21628175611 @default.

• next