Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162840905> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2162840905 endingPage "242" @default.
- W2162840905 startingPage "235" @default.
- W2162840905 abstract "SUMMARY Fresh human and bovine milk are bacteriostatic in vitro for only some (milk-sensitive) strains of E. coli. The addition of bicarbonate to the test system potentiates the bacteriostasis so that otherwise milk-resistant strains are inhibited. By titration of the bicarbonate in the milk, it is possible to determine the minimum concentration that will activate milk against a milk-resistant strain but be ineffective in boiled milk, i.e. it potentiates a heat-labile system in milk and does not merely exert a direct toxic effect. This concentration is lower for human milk than for cows‘ milk and can be reduced even further by the addition of more iron-binding protein. Lactoferrin and bicarbonate may be present in the gut of the newborn. In an attempt to imitate conditions in the infant gut, we therefore reinvestigated, in vitro and in the presence of added bicarbonate and transferrin, the bacteriostatic activity against E. coli of fresh breast-milk, commercial bottle-milk, and mixtures of these as fed to infants in this study. The results, and information about events in vivo deduced from the ratio of milk-sensitive to milk-resistant strains of E. coli isolated from babies‘ stools, suggest that neonatal intestinal secretions may contribute to the bacteriostatic activity of their feeds so that (1) in fully breastfed babies all strains of E. coli are inhibited to the same extent; there is no selection on the basis of milk sensitivity and equal numbers of strains resistant and sensitive to milk are found in the stools; (2) in fully bottle-fed babies E. coli is not inhibited since the milk is non-bacteriostatic and again there is no selection; (3) in babies fed at the breast but bottle-milk supplemented, only milk-sensitive strains are inhibited; milk-resistant strains are not, and preferentially colonize the large intestines." @default.
- W2162840905 created "2016-06-24" @default.
- W2162840905 creator A5015460073 @default.
- W2162840905 creator A5038635917 @default.
- W2162840905 creator A5041370554 @default.
- W2162840905 date "1977-04-01" @default.
- W2162840905 modified "2023-09-26" @default.
- W2162840905 title "Bacteriostasis ofEscherichia coliby milk: II. Effect of bicarbonate and transferrin on the activity of infant feeds" @default.
- W2162840905 cites W1512254479 @default.
- W2162840905 cites W1567706026 @default.
- W2162840905 cites W1592822001 @default.
- W2162840905 cites W1989034405 @default.
- W2162840905 cites W2002581726 @default.
- W2162840905 cites W2027616724 @default.
- W2162840905 cites W2036115032 @default.
- W2162840905 cites W2078584920 @default.
- W2162840905 cites W2092138868 @default.
- W2162840905 cites W2095152476 @default.
- W2162840905 cites W2109165370 @default.
- W2162840905 cites W2472015453 @default.
- W2162840905 cites W2501020464 @default.
- W2162840905 cites W82958360 @default.
- W2162840905 doi "https://doi.org/10.1017/s0022172400056126" @default.
- W2162840905 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2129835" @default.
- W2162840905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/321677" @default.
- W2162840905 hasPublicationYear "1977" @default.
- W2162840905 type Work @default.
- W2162840905 sameAs 2162840905 @default.
- W2162840905 citedByCount "17" @default.
- W2162840905 countsByYear W21628409052013 @default.
- W2162840905 crossrefType "journal-article" @default.
- W2162840905 hasAuthorship W2162840905A5015460073 @default.
- W2162840905 hasAuthorship W2162840905A5038635917 @default.
- W2162840905 hasAuthorship W2162840905A5041370554 @default.
- W2162840905 hasBestOaLocation W21628409051 @default.
- W2162840905 hasConcept C178790620 @default.
- W2162840905 hasConcept C185592680 @default.
- W2162840905 hasConcept C202751555 @default.
- W2162840905 hasConcept C22814914 @default.
- W2162840905 hasConcept C2775871700 @default.
- W2162840905 hasConcept C2779170986 @default.
- W2162840905 hasConcept C2781112554 @default.
- W2162840905 hasConcept C2992940123 @default.
- W2162840905 hasConcept C31903555 @default.
- W2162840905 hasConcept C55493867 @default.
- W2162840905 hasConcept C86803240 @default.
- W2162840905 hasConcept C89423630 @default.
- W2162840905 hasConceptScore W2162840905C178790620 @default.
- W2162840905 hasConceptScore W2162840905C185592680 @default.
- W2162840905 hasConceptScore W2162840905C202751555 @default.
- W2162840905 hasConceptScore W2162840905C22814914 @default.
- W2162840905 hasConceptScore W2162840905C2775871700 @default.
- W2162840905 hasConceptScore W2162840905C2779170986 @default.
- W2162840905 hasConceptScore W2162840905C2781112554 @default.
- W2162840905 hasConceptScore W2162840905C2992940123 @default.
- W2162840905 hasConceptScore W2162840905C31903555 @default.
- W2162840905 hasConceptScore W2162840905C55493867 @default.
- W2162840905 hasConceptScore W2162840905C86803240 @default.
- W2162840905 hasConceptScore W2162840905C89423630 @default.
- W2162840905 hasIssue "2" @default.
- W2162840905 hasLocation W21628409051 @default.
- W2162840905 hasLocation W21628409052 @default.
- W2162840905 hasLocation W21628409053 @default.
- W2162840905 hasLocation W21628409054 @default.
- W2162840905 hasOpenAccess W2162840905 @default.
- W2162840905 hasPrimaryLocation W21628409051 @default.
- W2162840905 hasRelatedWork W2002464088 @default.
- W2162840905 hasRelatedWork W2015126085 @default.
- W2162840905 hasRelatedWork W2037451891 @default.
- W2162840905 hasRelatedWork W2044919312 @default.
- W2162840905 hasRelatedWork W2097339088 @default.
- W2162840905 hasRelatedWork W2119580978 @default.
- W2162840905 hasRelatedWork W2162840905 @default.
- W2162840905 hasRelatedWork W2597915258 @default.
- W2162840905 hasRelatedWork W3151077204 @default.
- W2162840905 hasRelatedWork W82958360 @default.
- W2162840905 hasVolume "78" @default.
- W2162840905 isParatext "false" @default.
- W2162840905 isRetracted "false" @default.
- W2162840905 magId "2162840905" @default.
- W2162840905 workType "article" @default.