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• W2162845988 endingPage "1161" @default.
• W2162845988 startingPage "1152" @default.
• W2162845988 abstract "The assessment of percutaneous permeation of molecules is one of the main steps in the initial design and later in the evaluation of dermal or transdermal drug delivery systems. The literature reports numerous ex vivo , in vitro and in vivo models used to determine drug skin permeation profiles and kinetic parameters, some studies focusing on the correlation of the data obtained using these models with the dermal/transdermal absorption in humans. This paper reviews work from in vitro permeation studies to clinical performance, presenting various experimental models used in dermal/transdermal research, including the use of excised human or animal skin, cultured skin equivalents and animals. Studies focusing on transdermal absorption of a series of drug molecules and various delivery systems as well as mathematical models for skin absorption are reviewed." @default.
• W2162845988 created "2016-06-24" @default.
• W2162845988 creator A5061286862 @default.
• W2162845988 creator A5068630558 @default.
• W2162845988 date "2007-09-30" @default.
• W2162845988 modified "2023-09-29" @default.
• W2162845988 title "Transdermal skin delivery: Predictions for humans from in vivo, ex vivo and animal models☆" @default.
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• W2162845988 doi "https://doi.org/10.1016/j.addr.2007.07.004" @default.
• W2162845988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17889400" @default.
• W2162845988 hasPublicationYear "2007" @default.
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