FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162858999> ?p ?o ?g. }

• W2162858999 endingPage "89" @default.
• W2162858999 startingPage "81" @default.
• W2162858999 abstract "Background and objective While paracetamol exposure in pregnancy and early infancy has been associated with asthma, it remains unclear whether this is confounded by respiratory tract infections, which have been suggested as an alternative explanation. We undertook a systematic review and meta-analysis of longitudinal studies that reported the association between paracetamol exposure during pregnancy or infancy and the subsequent development of childhood asthma (≥5 years). Methods Two independent researchers searched the databases EMBASE and PUBMED on 12 August 2013 for relevant articles using predefined inclusion and exclusion criteria. Study quality was assessed and results were pooled using fixed effect models or random effect models when moderate between-study heterogeneity was observed. We explicitly assessed whether the observed associations are due to confounding by respiratory tract infections. Results Eleven observational cohort studies met the inclusion criteria. Any paracetamol use during the first trimester was related to increased risk of childhood asthma (5 studies, pooled OR=1.39, 95% CI 1.01 to 1.91) but there was marked between-study heterogeneity (I 2 =63%) and only one of these studies adjusted for maternal respiratory tract infections. Increasing frequency of use of paracetamol during infancy was associated with increased odds of childhood asthma (3 studies, pooled OR=1.15, 95% CI 1.00 to 1.31 per doubling of days exposure), but in these same three studies adjusting for respiratory tract infections reduced this association (OR=1.06, 95% CI 0.92 to 1.22). Discussion The association during early pregnancy exposure was highly variable between studies and exposure during infancy appears to be moderately confounded by respiratory tract infections. There is insufficient evidence to warrant changing guidelines on early life paracetamol exposure at this time." @default.
• W2162858999 created "2016-06-24" @default.
• W2162858999 creator A5005930688 @default.
• W2162858999 creator A5015119406 @default.
• W2162858999 creator A5046688127 @default.
• W2162858999 creator A5052537138 @default.
• W2162858999 creator A5066626261 @default.
• W2162858999 creator A5067224066 @default.
• W2162858999 creator A5086062766 @default.
• W2162858999 date "2014-11-26" @default.
• W2162858999 modified "2023-10-06" @default.
• W2162858999 title "Paracetamol exposure in pregnancy and early childhood and development of childhood asthma: a systematic review and meta-analysis" @default.
• W2162858999 cites W1480505726 @default.
• W2162858999 cites W1494713997 @default.
• W2162858999 cites W1937021287 @default.
• W2162858999 cites W1967015536 @default.
• W2162858999 cites W1969588824 @default.
• W2162858999 cites W1974726848 @default.
• W2162858999 cites W1979183973 @default.
• W2162858999 cites W1979423827 @default.
• W2162858999 cites W1983530509 @default.
• W2162858999 cites W1989196190 @default.
• W2162858999 cites W1991977103 @default.
• W2162858999 cites W2005501262 @default.
• W2162858999 cites W2012696672 @default.
• W2162858999 cites W2013196601 @default.
• W2162858999 cites W2029099730 @default.
• W2162858999 cites W2030061827 @default.
• W2162858999 cites W2030474337 @default.
• W2162858999 cites W2031049963 @default.
• W2162858999 cites W2033109965 @default.
• W2162858999 cites W2040108556 @default.
• W2162858999 cites W2040870202 @default.
• W2162858999 cites W2043990114 @default.
• W2162858999 cites W2061760124 @default.
• W2162858999 cites W2062293612 @default.
• W2162858999 cites W2076239759 @default.
• W2162858999 cites W2091667585 @default.
• W2162858999 cites W2096425196 @default.
• W2162858999 cites W2118741928 @default.
• W2162858999 cites W2120168460 @default.
• W2162858999 cites W2120793327 @default.
• W2162858999 cites W2121090867 @default.
• W2162858999 cites W2122288171 @default.
• W2162858999 cites W2125178177 @default.
• W2162858999 cites W2125435699 @default.
• W2162858999 cites W2127048208 @default.
• W2162858999 cites W2128133006 @default.
• W2162858999 cites W2129062531 @default.
• W2162858999 cites W2129447215 @default.
• W2162858999 cites W2130345799 @default.
• W2162858999 cites W2131439159 @default.
• W2162858999 cites W2136480859 @default.
• W2162858999 cites W2138421921 @default.
• W2162858999 cites W2155287094 @default.
• W2162858999 cites W2160256447 @default.
• W2162858999 cites W2161840968 @default.
• W2162858999 cites W2168859479 @default.
• W2162858999 cites W2312397711 @default.
• W2162858999 cites W2323730721 @default.
• W2162858999 cites W4300851943 @default.
• W2162858999 cites W8747624 @default.
• W2162858999 doi "https://doi.org/10.1136/archdischild-2012-303043" @default.
• W2162858999 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25429049" @default.
• W2162858999 hasPublicationYear "2014" @default.
• W2162858999 type Work @default.
• W2162858999 sameAs 2162858999 @default.
• W2162858999 citedByCount "83" @default.
• W2162858999 countsByYear W21628589992014 @default.
• W2162858999 countsByYear W21628589992015 @default.
• W2162858999 countsByYear W21628589992016 @default.
• W2162858999 countsByYear W21628589992017 @default.
• W2162858999 countsByYear W21628589992018 @default.
• W2162858999 countsByYear W21628589992019 @default.
• W2162858999 countsByYear W21628589992020 @default.
• W2162858999 countsByYear W21628589992021 @default.
• W2162858999 countsByYear W21628589992022 @default.
• W2162858999 countsByYear W21628589992023 @default.
• W2162858999 crossrefType "journal-article" @default.
• W2162858999 hasAuthorship W2162858999A5005930688 @default.
• W2162858999 hasAuthorship W2162858999A5015119406 @default.
• W2162858999 hasAuthorship W2162858999A5046688127 @default.
• W2162858999 hasAuthorship W2162858999A5052537138 @default.
• W2162858999 hasAuthorship W2162858999A5066626261 @default.
• W2162858999 hasAuthorship W2162858999A5067224066 @default.
• W2162858999 hasAuthorship W2162858999A5086062766 @default.
• W2162858999 hasBestOaLocation W21628589992 @default.
• W2162858999 hasConcept C126322002 @default.
• W2162858999 hasConcept C156957248 @default.
• W2162858999 hasConcept C187212893 @default.
• W2162858999 hasConcept C201903717 @default.
• W2162858999 hasConcept C23131810 @default.
• W2162858999 hasConcept C2776012195 @default.
• W2162858999 hasConcept C2776042228 @default.
• W2162858999 hasConcept C2779234561 @default.
• W2162858999 hasConcept C534529494 @default.
• W2162858999 hasConcept C54355233 @default.
• W2162858999 hasConcept C71924100 @default.

• next