FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162859269> ?p ?o ?g. }

• W2162859269 endingPage "055002" @default.
• W2162859269 startingPage "055002" @default.
• W2162859269 abstract "Molecular interactions of optical clearing agents were investigated using a combination of molecular dynamics (MD) simulations and optical spectroscopy. For a series of sugar alcohols with low to high optical clearing potential, Raman spectroscopy and integrating sphere measurements were used to quantitatively characterize tissue water loss and reduction in light scattering following agent exposures. The rate of tissue water loss was found to correlate with agent optical clearing potential, but equivalent tissue optical clearing was measured in native and fixed tissue in vitro, given long-enough exposure times to the polyol series. MD simulations showed that the rate of tissue optical clearing correlated with the preferential formation of hydrogen bond bridges between agent and collagen. Hydrogen bond bridge formation disrupts the collagen hydration layer and facilitates replacement by a chemical agent to homogenize tissue refractive index. However, the reduction in tissue light scattering did not correlate with the agent index of refraction. Our results suggest that a necessary property of optical clearing agents is hyperosmolarity to tissue, but that the most effective agents with the highest rates of optical clearing are a subset with the highest collagen solubilities." @default.
• W2162859269 created "2016-06-24" @default.
• W2162859269 creator A5019444941 @default.
• W2162859269 creator A5029566831 @default.
• W2162859269 creator A5033622450 @default.
• W2162859269 creator A5061603084 @default.
• W2162859269 date "2010-01-01" @default.
• W2162859269 modified "2023-09-26" @default.
• W2162859269 title "Molecular basis for optical clearing of collagenous tissues" @default.
• W2162859269 cites W102588265 @default.
• W2162859269 cites W1890886311 @default.
• W2162859269 cites W1966905725 @default.
• W2162859269 cites W1969810415 @default.
• W2162859269 cites W1972881060 @default.
• W2162859269 cites W1995577222 @default.
• W2162859269 cites W1997120927 @default.
• W2162859269 cites W2003674624 @default.
• W2162859269 cites W2005746614 @default.
• W2162859269 cites W2018041784 @default.
• W2162859269 cites W2018619515 @default.
• W2162859269 cites W2031027749 @default.
• W2162859269 cites W2032714412 @default.
• W2162859269 cites W2038997089 @default.
• W2162859269 cites W2039638056 @default.
• W2162859269 cites W2041402205 @default.
• W2162859269 cites W2042555832 @default.
• W2162859269 cites W2042563627 @default.
• W2162859269 cites W2068318144 @default.
• W2162859269 cites W2090510037 @default.
• W2162859269 cites W2102376488 @default.
• W2162859269 cites W2107317356 @default.
• W2162859269 cites W2121084374 @default.
• W2162859269 cites W2130710690 @default.
• W2162859269 cites W2132262459 @default.
• W2162859269 cites W2137676479 @default.
• W2162859269 cites W2162139225 @default.
• W2162859269 cites W2169015628 @default.
• W2162859269 cites W408617622 @default.
• W2162859269 doi "https://doi.org/10.1117/1.3484748" @default.
• W2162859269 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21054084" @default.
• W2162859269 hasPublicationYear "2010" @default.
• W2162859269 type Work @default.
• W2162859269 sameAs 2162859269 @default.
• W2162859269 citedByCount "64" @default.
• W2162859269 countsByYear W21628592692012 @default.
• W2162859269 countsByYear W21628592692013 @default.
• W2162859269 countsByYear W21628592692014 @default.
• W2162859269 countsByYear W21628592692015 @default.
• W2162859269 countsByYear W21628592692016 @default.
• W2162859269 countsByYear W21628592692017 @default.
• W2162859269 countsByYear W21628592692018 @default.
• W2162859269 countsByYear W21628592692019 @default.
• W2162859269 countsByYear W21628592692020 @default.
• W2162859269 countsByYear W21628592692021 @default.
• W2162859269 countsByYear W21628592692022 @default.
• W2162859269 countsByYear W21628592692023 @default.
• W2162859269 crossrefType "journal-article" @default.
• W2162859269 hasAuthorship W2162859269A5019444941 @default.
• W2162859269 hasAuthorship W2162859269A5029566831 @default.
• W2162859269 hasAuthorship W2162859269A5033622450 @default.
• W2162859269 hasAuthorship W2162859269A5061603084 @default.
• W2162859269 hasBestOaLocation W21628592691 @default.
• W2162859269 hasConcept C112887158 @default.
• W2162859269 hasConcept C120456961 @default.
• W2162859269 hasConcept C120665830 @default.
• W2162859269 hasConcept C121332964 @default.
• W2162859269 hasConcept C12554922 @default.
• W2162859269 hasConcept C14631669 @default.
• W2162859269 hasConcept C155672457 @default.
• W2162859269 hasConcept C171250308 @default.
• W2162859269 hasConcept C178790620 @default.
• W2162859269 hasConcept C185592680 @default.
• W2162859269 hasConcept C191486275 @default.
• W2162859269 hasConcept C192562407 @default.
• W2162859269 hasConcept C32909587 @default.
• W2162859269 hasConcept C40003534 @default.
• W2162859269 hasConcept C86803240 @default.
• W2162859269 hasConceptScore W2162859269C112887158 @default.
• W2162859269 hasConceptScore W2162859269C120456961 @default.
• W2162859269 hasConceptScore W2162859269C120665830 @default.
• W2162859269 hasConceptScore W2162859269C121332964 @default.
• W2162859269 hasConceptScore W2162859269C12554922 @default.
• W2162859269 hasConceptScore W2162859269C14631669 @default.
• W2162859269 hasConceptScore W2162859269C155672457 @default.
• W2162859269 hasConceptScore W2162859269C171250308 @default.
• W2162859269 hasConceptScore W2162859269C178790620 @default.
• W2162859269 hasConceptScore W2162859269C185592680 @default.
• W2162859269 hasConceptScore W2162859269C191486275 @default.
• W2162859269 hasConceptScore W2162859269C192562407 @default.
• W2162859269 hasConceptScore W2162859269C32909587 @default.
• W2162859269 hasConceptScore W2162859269C40003534 @default.
• W2162859269 hasConceptScore W2162859269C86803240 @default.
• W2162859269 hasIssue "5" @default.
• W2162859269 hasLocation W21628592691 @default.
• W2162859269 hasLocation W21628592692 @default.
• W2162859269 hasOpenAccess W2162859269 @default.
• W2162859269 hasPrimaryLocation W21628592691 @default.
• W2162859269 hasRelatedWork W1908432545 @default.

• next