Matches in SemOpenAlex for { <https://semopenalex.org/work/W2162869036> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2162869036 abstract "Viscoelastic Response (VisR) imaging is an acoustic radiation force (ARF)-based ultrasonic technique for estimating the viscoelastic properties of tissue. It has been proposed as a method for monitoring degeneration in the skeletal muscles of boys with Duchenne muscular dystrophy (DMD). DMD causes progressive inflammation, necrosis, fibrosis and fatty deposition in muscle, all of which will alter the elasticity and viscosity of the tissue. The motivation of this work is to investigate VisR's potential as method for monitoring dystrophic muscle degeneration, in vivo, in boys with DMD. In an ongoing longitudinal clinical study, muscles in the lower limbs of boys affected with DMD and age-matched healthy control boys are imaged using VisR thrice yearly for four years. A case study of serial imaging results in the Medial Gastrocnemius (GM) muscle of one boy with DMD is herein presented. Beginning at age 6.2 years, parametric VisR images of τ, or the ratio of viscosity to elasticity, show a growing region of high τ (>1.2 ms) over the span of one year. This result is consistent with expected progressive inflammation and fatty deposition early in the GM's degenerative cycle. Over the course of the next four months, the area of high τ decreases, which is in agreement with the expected onset of muscle fibrosis. Then, at age 8.3 years, small and diffusely distributed high τ regions are observed in the muscle, consistent with expected distributed fatty depositions. These results suggest that VisR, a noninvasive ultrasound imaging method, may be clinically viable for monitoring local muscular compositional and structural changes associated with dystrophic degeneration, in vivo." @default.
- W2162869036 created "2016-06-24" @default.
- W2162869036 creator A5005964218 @default.
- W2162869036 creator A5015784672 @default.
- W2162869036 creator A5027221074 @default.
- W2162869036 creator A5036542525 @default.
- W2162869036 creator A5067484626 @default.
- W2162869036 creator A5068248964 @default.
- W2162869036 creator A5074142135 @default.
- W2162869036 creator A5087891309 @default.
- W2162869036 date "2015-10-01" @default.
- W2162869036 modified "2023-09-22" @default.
- W2162869036 title "Viscoelastic Response (VisR) assessment of longitudinal dystrophic degeneration in clinical Duchenne muscular dystrophy" @default.
- W2162869036 cites W1968240102 @default.
- W2162869036 cites W1972367999 @default.
- W2162869036 cites W1988501930 @default.
- W2162869036 cites W1995260577 @default.
- W2162869036 cites W2008660959 @default.
- W2162869036 cites W2024991751 @default.
- W2162869036 cites W2037286164 @default.
- W2162869036 cites W2044638869 @default.
- W2162869036 cites W2066180106 @default.
- W2162869036 cites W2094029513 @default.
- W2162869036 cites W2142998658 @default.
- W2162869036 cites W2143595830 @default.
- W2162869036 cites W2162004782 @default.
- W2162869036 cites W2164481873 @default.
- W2162869036 doi "https://doi.org/10.1109/ultsym.2015.0225" @default.
- W2162869036 hasPublicationYear "2015" @default.
- W2162869036 type Work @default.
- W2162869036 sameAs 2162869036 @default.
- W2162869036 citedByCount "3" @default.
- W2162869036 countsByYear W21628690362016 @default.
- W2162869036 countsByYear W21628690362017 @default.
- W2162869036 countsByYear W21628690362021 @default.
- W2162869036 crossrefType "proceedings-article" @default.
- W2162869036 hasAuthorship W2162869036A5005964218 @default.
- W2162869036 hasAuthorship W2162869036A5015784672 @default.
- W2162869036 hasAuthorship W2162869036A5027221074 @default.
- W2162869036 hasAuthorship W2162869036A5036542525 @default.
- W2162869036 hasAuthorship W2162869036A5067484626 @default.
- W2162869036 hasAuthorship W2162869036A5068248964 @default.
- W2162869036 hasAuthorship W2162869036A5074142135 @default.
- W2162869036 hasAuthorship W2162869036A5087891309 @default.
- W2162869036 hasConcept C126322002 @default.
- W2162869036 hasConcept C126838900 @default.
- W2162869036 hasConcept C142724271 @default.
- W2162869036 hasConcept C143753070 @default.
- W2162869036 hasConcept C159985019 @default.
- W2162869036 hasConcept C186541917 @default.
- W2162869036 hasConcept C192562407 @default.
- W2162869036 hasConcept C2778943923 @default.
- W2162869036 hasConcept C2779030066 @default.
- W2162869036 hasConcept C2779354088 @default.
- W2162869036 hasConcept C2780559512 @default.
- W2162869036 hasConcept C71924100 @default.
- W2162869036 hasConceptScore W2162869036C126322002 @default.
- W2162869036 hasConceptScore W2162869036C126838900 @default.
- W2162869036 hasConceptScore W2162869036C142724271 @default.
- W2162869036 hasConceptScore W2162869036C143753070 @default.
- W2162869036 hasConceptScore W2162869036C159985019 @default.
- W2162869036 hasConceptScore W2162869036C186541917 @default.
- W2162869036 hasConceptScore W2162869036C192562407 @default.
- W2162869036 hasConceptScore W2162869036C2778943923 @default.
- W2162869036 hasConceptScore W2162869036C2779030066 @default.
- W2162869036 hasConceptScore W2162869036C2779354088 @default.
- W2162869036 hasConceptScore W2162869036C2780559512 @default.
- W2162869036 hasConceptScore W2162869036C71924100 @default.
- W2162869036 hasLocation W21628690361 @default.
- W2162869036 hasOpenAccess W2162869036 @default.
- W2162869036 hasPrimaryLocation W21628690361 @default.
- W2162869036 hasRelatedWork W1565774324 @default.
- W2162869036 hasRelatedWork W1861912616 @default.
- W2162869036 hasRelatedWork W1922964466 @default.
- W2162869036 hasRelatedWork W1975139695 @default.
- W2162869036 hasRelatedWork W1986179597 @default.
- W2162869036 hasRelatedWork W2004904112 @default.
- W2162869036 hasRelatedWork W2007288627 @default.
- W2162869036 hasRelatedWork W2025740753 @default.
- W2162869036 hasRelatedWork W2031490919 @default.
- W2162869036 hasRelatedWork W2132091723 @default.
- W2162869036 hasRelatedWork W2144181217 @default.
- W2162869036 hasRelatedWork W2320720071 @default.
- W2162869036 hasRelatedWork W2332533955 @default.
- W2162869036 hasRelatedWork W2741295588 @default.
- W2162869036 hasRelatedWork W2792139781 @default.
- W2162869036 hasRelatedWork W2908261451 @default.
- W2162869036 hasRelatedWork W3031270319 @default.
- W2162869036 hasRelatedWork W3085484828 @default.
- W2162869036 hasRelatedWork W3188939308 @default.
- W2162869036 hasRelatedWork W3208974406 @default.
- W2162869036 isParatext "false" @default.
- W2162869036 isRetracted "false" @default.
- W2162869036 magId "2162869036" @default.
- W2162869036 workType "article" @default.