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• W2162872299 abstract "A synthetic 23-amino acid peptide derived from the CH3 domain of human IgG1 was found to be a potent adjuvant as well as a polyclonal activator. The Fc peptide was found to enhance human and murine humoral, and T cell-mediated immune responses. Moreover, in vivo administration of Fc peptide enhanced murine natural killer cell activity. The synthetic Fc peptide was found to be more potent, on a molar basis, than native Fc fragments in inducing polyclonal antibody production and potentiating immune responses." @default.
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• W2162872299 date "1983-03-01" @default.
• W2162872299 modified "2023-10-11" @default.
• W2162872299 title "Synthetic Fc peptide-mediated regulation of the immune response. I. Characterization of the immunomodulating properties of a synthetic 23-amino acid peptide derived from the sequence of the CH3 domain of human IgG1." @default.
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• W2162872299 doi "https://doi.org/10.1084/jem.157.3.947" @default.
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