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• W2162916888 abstract "To evaluate the contribution of cytotoxic T-Iymphocyte antigen-4(CTLA-4)+49A/G polymorphism to the susceptibility to type-1 diabetes (T1D) in Turkish children.A case-control study was designed to include 91 Turkish children with T1D and 99 healthy controls. CTLA-4 (+99A/G) gene polymorphism typing was done by PCR amplification followed by restriction fragment length polymorphism method.The genotype and allele frequencies of the CTLA-4 (+99A/G)polymorphism in patients with T1D were not different from those in the controls (p>0.05). The allele frequency of G was 36.2% in patients with T1D,and 31.8% in controls (p>0.05). Additionally, this polymorphism was not associated with the clinical and laboratory characteristics of the patients with T1D (p>0.05).Our case-control study suggests that the CTLA-4 (+99A/G) gene polymorphism is not associated with T1D in the Turkish population." @default.
• W2162916888 created "2016-06-24" @default.
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• W2162916888 date "2013-03-05" @default.
• W2162916888 modified "2023-10-17" @default.
• W2162916888 title "CTLA-4 (+49A/G) Polymorphism and Type-1 Diabetes in Turkish Children" @default.
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• W2162916888 doi "https://doi.org/10.4274/jcrpe.879" @default.
• W2162916888 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3628391" @default.
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