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• W2163071306 endingPage "e2078" @default.
• W2163071306 startingPage "e2078" @default.
• W2163071306 abstract "Rhamnolipids are biosurfactants with potential for diversified industrial and environmental uses. The present study evaluated three strategies for increasing the production of rhamnolipid-type biosurfactants produced by Pseudomonas aeruginosa strain PA1. The influence of pH, the addition of P. aeruginosa spent culture medium and the use of a fed-batch process were examined. The culture medium adjusted to pH 7.0 was the most productive. Furthermore, the pH of the culture medium had a measurable effect on the ratio of synthesized mono- and dirhamnolipids. At pH values below 7.3, the proportion of monorhamnolipids decreased from 45 to 24%. The recycling of 20% of the spent culture medium in where P. aeruginosa was grown up to the later stationary phase was responsible for a 100% increase in rhamnolipid volumetric productivity in the new culture medium. Finally, the use of fed-batch operation under conditions of limited nitrogen resulted in a 3.8-fold increase in the amount of rhamnolipids produced (2.9 g L −1 –10.9 g L −1 ). These results offer promising pathways for the optimization of processes for the production of rhamnolipids." @default.
• W2163071306 created "2016-06-24" @default.
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• W2163071306 date "2016-05-24" @default.
• W2163071306 modified "2023-10-15" @default.
• W2163071306 title "Strategies for improved rhamnolipid production by<i>Pseudomonas aeruginosa</i>PA1" @default.
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• W2163071306 doi "https://doi.org/10.7717/peerj.2078" @default.
• W2163071306 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4888285" @default.
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