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- W2163129688 abstract "The key step of carcinogenesis is the malignant transformation which is fundamentally a telomere biology dysfunction permitting cells to bypass the Hayflick limit and to divide indefinitely and uncontrollably. Thus all partners and structures involved in normal and abnormal telomere maintenance, protection and lengthening can be considered as potential anti-cancer therapeutic targets. In this Point of View we discuss, highlight and provide new perspectives from the current knowledge and understanding to position the different aspects of telomere biology and dysfunction as diagnostic, preventive and curative tools in the field of cancer." @default.
- W2163129688 created "2016-06-24" @default.
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- W2163129688 date "2015-09-18" @default.
- W2163129688 modified "2023-10-01" @default.
- W2163129688 title "Telomere biology: Rationale for diagnostics and therapeutics in cancer" @default.
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- W2163129688 doi "https://doi.org/10.1080/15476286.2015.1081329" @default.
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