Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163130168> ?p ?o ?g. }
- W2163130168 endingPage "1075" @default.
- W2163130168 startingPage "1070" @default.
- W2163130168 abstract "To evaluate the efficacy and safety of long-term conservative therapy with medroxyprogesterone acetate (MPA) for endometrial carcinoma in young patients who had experienced failure after initial therapy or relapse, we reviewed the clinical and pathologic records of eight patients diagnosed with well-differentiated endometrial adenocarcinoma without myometrial invasion who were treated with MPA for over 6 months because of treatment failure or relapse.The average duration of MPA treatment was 22 months. All patients were followed-up for a mean of 76.5 months. Seven patients responded to initial MPA treatment within a period of 14 months (mean, 7.9 months). All these patients experienced relapse and the mean time to relapse was 11.6 months (range, 4-33 months). All six patients with relapse were treated with additional treatments of MPA, and all but one responded to this treatment within a period of 16 months (mean, 8.0 months). Six patients ultimately underwent hysterectomy. All presented well-differentiated endometrioid adenocarcinomas without extrauterine disease. Three became pregnant and two delivered full-term normal infants. No patient died of the disease.Although lesions are expected to disappear with prolonged MPA treatment, this form of progestin therapy is hazardous because recurrence occurs frequently. Only strictly selected patients should therefore be indicated for long-term MPA treatment and careful evaluation before and after treatment should be performed." @default.
- W2163130168 created "2016-06-24" @default.
- W2163130168 creator A5010889533 @default.
- W2163130168 creator A5016208556 @default.
- W2163130168 creator A5065798646 @default.
- W2163130168 creator A5090995829 @default.
- W2163130168 date "2005-12-16" @default.
- W2163130168 modified "2023-10-06" @default.
- W2163130168 title "Long-term conservative therapy for endometrial adenocarcinoma in young women" @default.
- W2163130168 cites W1933506009 @default.
- W2163130168 cites W1968400287 @default.
- W2163130168 cites W1979945461 @default.
- W2163130168 cites W1987338754 @default.
- W2163130168 cites W1990763909 @default.
- W2163130168 cites W1992111987 @default.
- W2163130168 cites W2016232075 @default.
- W2163130168 cites W2016413256 @default.
- W2163130168 cites W2046242509 @default.
- W2163130168 cites W2047111383 @default.
- W2163130168 cites W2050621827 @default.
- W2163130168 cites W2056439076 @default.
- W2163130168 cites W2061924794 @default.
- W2163130168 cites W2064617101 @default.
- W2163130168 cites W2064727568 @default.
- W2163130168 cites W2069547854 @default.
- W2163130168 cites W2074080493 @default.
- W2163130168 cites W2085757399 @default.
- W2163130168 cites W2086713990 @default.
- W2163130168 cites W2088666200 @default.
- W2163130168 cites W2134597221 @default.
- W2163130168 cites W2140061607 @default.
- W2163130168 cites W2144173857 @default.
- W2163130168 cites W2169539268 @default.
- W2163130168 doi "https://doi.org/10.1093/humrep/dei434" @default.
- W2163130168 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16361282" @default.
- W2163130168 hasPublicationYear "2005" @default.
- W2163130168 type Work @default.
- W2163130168 sameAs 2163130168 @default.
- W2163130168 citedByCount "66" @default.
- W2163130168 countsByYear W21631301682012 @default.
- W2163130168 countsByYear W21631301682013 @default.
- W2163130168 countsByYear W21631301682014 @default.
- W2163130168 countsByYear W21631301682015 @default.
- W2163130168 countsByYear W21631301682016 @default.
- W2163130168 countsByYear W21631301682017 @default.
- W2163130168 countsByYear W21631301682018 @default.
- W2163130168 countsByYear W21631301682019 @default.
- W2163130168 countsByYear W21631301682020 @default.
- W2163130168 countsByYear W21631301682021 @default.
- W2163130168 countsByYear W21631301682023 @default.
- W2163130168 crossrefType "journal-article" @default.
- W2163130168 hasAuthorship W2163130168A5010889533 @default.
- W2163130168 hasAuthorship W2163130168A5016208556 @default.
- W2163130168 hasAuthorship W2163130168A5065798646 @default.
- W2163130168 hasAuthorship W2163130168A5090995829 @default.
- W2163130168 hasBestOaLocation W21631301681 @default.
- W2163130168 hasConcept C121608353 @default.
- W2163130168 hasConcept C126322002 @default.
- W2163130168 hasConcept C141071460 @default.
- W2163130168 hasConcept C2775934596 @default.
- W2163130168 hasConcept C2776306185 @default.
- W2163130168 hasConcept C2776607906 @default.
- W2163130168 hasConcept C2777088508 @default.
- W2163130168 hasConcept C2777164284 @default.
- W2163130168 hasConcept C2779494336 @default.
- W2163130168 hasConcept C2779742232 @default.
- W2163130168 hasConcept C2781182431 @default.
- W2163130168 hasConcept C71924100 @default.
- W2163130168 hasConceptScore W2163130168C121608353 @default.
- W2163130168 hasConceptScore W2163130168C126322002 @default.
- W2163130168 hasConceptScore W2163130168C141071460 @default.
- W2163130168 hasConceptScore W2163130168C2775934596 @default.
- W2163130168 hasConceptScore W2163130168C2776306185 @default.
- W2163130168 hasConceptScore W2163130168C2776607906 @default.
- W2163130168 hasConceptScore W2163130168C2777088508 @default.
- W2163130168 hasConceptScore W2163130168C2777164284 @default.
- W2163130168 hasConceptScore W2163130168C2779494336 @default.
- W2163130168 hasConceptScore W2163130168C2779742232 @default.
- W2163130168 hasConceptScore W2163130168C2781182431 @default.
- W2163130168 hasConceptScore W2163130168C71924100 @default.
- W2163130168 hasIssue "4" @default.
- W2163130168 hasLocation W21631301681 @default.
- W2163130168 hasLocation W21631301682 @default.
- W2163130168 hasOpenAccess W2163130168 @default.
- W2163130168 hasPrimaryLocation W21631301681 @default.
- W2163130168 hasRelatedWork W114650669 @default.
- W2163130168 hasRelatedWork W1588051095 @default.
- W2163130168 hasRelatedWork W1980959075 @default.
- W2163130168 hasRelatedWork W2027462169 @default.
- W2163130168 hasRelatedWork W2038265094 @default.
- W2163130168 hasRelatedWork W2282112325 @default.
- W2163130168 hasRelatedWork W2365765378 @default.
- W2163130168 hasRelatedWork W2396416709 @default.
- W2163130168 hasRelatedWork W33030245 @default.
- W2163130168 hasRelatedWork W4211148452 @default.
- W2163130168 hasVolume "21" @default.
- W2163130168 isParatext "false" @default.
- W2163130168 isRetracted "false" @default.