FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163231489> ?p ?o ?g. }

• W2163231489 endingPage "1193" @default.
• W2163231489 startingPage "1188" @default.
• W2163231489 abstract "<b>Background:</b> A previous pilot study showed that early arrival time of a microbubble in a hepatic vein is a sensitive indicator of cirrhosis. <b>Aim:</b> To see if this index can also grade diffuse liver disease. <b>Patients:</b> Thirty nine fasted patients with histologically characterised disease were studied prospectively. Nine patients had no evidence of liver fibrosis, 10 had fibrosis without cirrhosis, and 20 had cirrhosis (five Child’s A, seven Child’s B, and eight Child’s C). <b>Methods:</b> Bolus injections of a microbubble (Levovist; Schering, Berlin) were given intravenously, followed by a saline flush. Time intensity curves of hepatic vein and carotid artery spectral Doppler signals were analysed. Hepatic vein transit time (HVTT) was calculated as the time after injection at which a sustained signal increase >10% of baseline was seen. Carotid delay time (CDT) was calculated as the difference between carotid and hepatic vein enhancement. <b>Results:</b> Diagnostic studies were achieved in 38/39 subjects. Both HVTT and CDT became consistently shorter with worsening disease, as follows (means (SD)): HVTT: no fibrosis 44 (25) s, fibrosis 26 (8) s, Child’s A 21 (1) s, Child’s B 16 (3) s, and Child’s C 16 (2) s; CDT: no fibrosis 31 (29) s, fibrosis 14 (6) s, Child’s A 8 (1) s, Child’s B 4 (4) s, and Child’s C 3 (3) s. These differences were highly significant (p<0.001, ANOVA comparison). A HVTT <24 s and a CDT <10 s were 100% sensitive for cirrhosis (20/20 and 18/18, respectively) but not completely specific: 2/8 subjects with fibrosis had CDT values <10 s and 3/9 had HVTT <24 s. <b>Conclusion:</b> This minimally invasive test shows promise not only in diagnosing cirrhosis but also in assessing disease severity." @default.
• W2163231489 created "2016-06-24" @default.
• W2163231489 creator A5019080190 @default.
• W2163231489 date "2003-08-01" @default.
• W2163231489 modified "2023-09-24" @default.
• W2163231489 title "Liver microbubble transit time compared with histology and Child-Pugh score in diffuse liver disease: a cross sectional study" @default.
• W2163231489 cites W1497715925 @default.
• W2163231489 cites W1577694822 @default.
• W2163231489 cites W1932743671 @default.
• W2163231489 cites W1981900811 @default.
• W2163231489 cites W1987854290 @default.
• W2163231489 cites W1999836143 @default.
• W2163231489 cites W2002498341 @default.
• W2163231489 cites W2017728177 @default.
• W2163231489 cites W2035699138 @default.
• W2163231489 cites W2052238540 @default.
• W2163231489 cites W2054109759 @default.
• W2163231489 cites W2095337268 @default.
• W2163231489 cites W2096866291 @default.
• W2163231489 cites W2118715583 @default.
• W2163231489 cites W2134005006 @default.
• W2163231489 cites W2164864100 @default.
• W2163231489 cites W2172076494 @default.
• W2163231489 cites W2401121339 @default.
• W2163231489 cites W8277583 @default.
• W2163231489 doi "https://doi.org/10.1136/gut.52.8.1188" @default.
• W2163231489 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1773750" @default.
• W2163231489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12865280" @default.
• W2163231489 hasPublicationYear "2003" @default.
• W2163231489 type Work @default.
• W2163231489 sameAs 2163231489 @default.
• W2163231489 citedByCount "110" @default.
• W2163231489 countsByYear W21632314892012 @default.
• W2163231489 countsByYear W21632314892013 @default.
• W2163231489 countsByYear W21632314892014 @default.
• W2163231489 countsByYear W21632314892015 @default.
• W2163231489 countsByYear W21632314892016 @default.
• W2163231489 countsByYear W21632314892017 @default.
• W2163231489 countsByYear W21632314892018 @default.
• W2163231489 countsByYear W21632314892019 @default.
• W2163231489 countsByYear W21632314892021 @default.
• W2163231489 countsByYear W21632314892022 @default.
• W2163231489 crossrefType "journal-article" @default.
• W2163231489 hasAuthorship W2163231489A5019080190 @default.
• W2163231489 hasBestOaLocation W21632314891 @default.
• W2163231489 hasConcept C126322002 @default.
• W2163231489 hasConcept C126838900 @default.
• W2163231489 hasConcept C127413603 @default.
• W2163231489 hasConcept C143753070 @default.
• W2163231489 hasConcept C22212356 @default.
• W2163231489 hasConcept C2776938444 @default.
• W2163231489 hasConcept C2777075537 @default.
• W2163231489 hasConcept C2777214474 @default.
• W2163231489 hasConcept C2780559512 @default.
• W2163231489 hasConcept C3018129524 @default.
• W2163231489 hasConcept C43376680 @default.
• W2163231489 hasConcept C71924100 @default.
• W2163231489 hasConcept C90924648 @default.
• W2163231489 hasConceptScore W2163231489C126322002 @default.
• W2163231489 hasConceptScore W2163231489C126838900 @default.
• W2163231489 hasConceptScore W2163231489C127413603 @default.
• W2163231489 hasConceptScore W2163231489C143753070 @default.
• W2163231489 hasConceptScore W2163231489C22212356 @default.
• W2163231489 hasConceptScore W2163231489C2776938444 @default.
• W2163231489 hasConceptScore W2163231489C2777075537 @default.
• W2163231489 hasConceptScore W2163231489C2777214474 @default.
• W2163231489 hasConceptScore W2163231489C2780559512 @default.
• W2163231489 hasConceptScore W2163231489C3018129524 @default.
• W2163231489 hasConceptScore W2163231489C43376680 @default.
• W2163231489 hasConceptScore W2163231489C71924100 @default.
• W2163231489 hasConceptScore W2163231489C90924648 @default.
• W2163231489 hasIssue "8" @default.
• W2163231489 hasLocation W21632314891 @default.
• W2163231489 hasLocation W21632314892 @default.
• W2163231489 hasLocation W21632314893 @default.
• W2163231489 hasLocation W21632314894 @default.
• W2163231489 hasLocation W21632314895 @default.
• W2163231489 hasOpenAccess W2163231489 @default.
• W2163231489 hasPrimaryLocation W21632314891 @default.
• W2163231489 hasRelatedWork W103547024 @default.
• W2163231489 hasRelatedWork W1731674693 @default.
• W2163231489 hasRelatedWork W1966263252 @default.
• W2163231489 hasRelatedWork W2043383895 @default.
• W2163231489 hasRelatedWork W2104682956 @default.
• W2163231489 hasRelatedWork W2110243916 @default.
• W2163231489 hasRelatedWork W2370602281 @default.
• W2163231489 hasRelatedWork W2382531208 @default.
• W2163231489 hasRelatedWork W2418776627 @default.
• W2163231489 hasRelatedWork W2603200842 @default.
• W2163231489 hasVolume "52" @default.
• W2163231489 isParatext "false" @default.
• W2163231489 isRetracted "false" @default.
• W2163231489 magId "2163231489" @default.
• W2163231489 workType "article" @default.