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- W2163255306 abstract "Although thyroid nodules are common, few are malignant and require surgical treatment. A systematic approach to their evaluation is important to avoid unnecessary surgery. Fine-needle aspiration biopsy has resulted in substantial improvements in diagnostic accuracy, cost reductions, and higher malignancy yield at time of surgery. The preferred approach when repeated fine-needle aspiration biopsy fails to yield an adequate specimen remains a challenge. Management of patients with nodules “suspicious for follicular neoplasm” is difficult, since only 15% to 20% of such lesions have been shown to be malignant. Immunohistochemical markers, such as galectin-3 and human bone marrow endothelial cell (HBME-1), have shown promise in preliminary studies. Routine calcitonin measurement in patients with thyroid nodules has been advocated for early detection of medullary thyroid cancer. However, the low frequency of this cancer, coupled with the high cost associated with case detection, has resulted in a lack of general acceptance of this recommendation." @default.
- W2163255306 created "2016-06-24" @default.
- W2163255306 creator A5011038225 @default.
- W2163255306 creator A5015687387 @default.
- W2163255306 date "2005-06-07" @default.
- W2163255306 modified "2023-10-16" @default.
- W2163255306 title "Continuing Controversies in the Management of Thyroid Nodules" @default.
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- W2163255306 doi "https://doi.org/10.7326/0003-4819-142-11-200506070-00011" @default.
- W2163255306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15941700" @default.
- W2163255306 hasPublicationYear "2005" @default.
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