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- W2163280318 abstract "We investigated the effect of varying laser parameters on ablation rate and consecutive thermal damage of Tm:YAG (2.014pm) and Ho:YAG (2.130pm) lasers. Mid-infrared wavelengths are strongly absorbed by most biological tissues due to high water content. The water vapor filled cavitation bubbles created and sustained by a mid-infrared laser pulse enables the laser beam to penetrate a depth far beyond the absorption depth in aqueous fluids and to reach remote targets (1,2). Collapse and rebound of cavitation bubbles are capable of generating high pressure and temperature transients (3). Ablation rate was defined as the ratio of number of laser pulses required to perforate a tissue sample to its thickness, micron/pulse(pm/p). The ablation rate of fresh bovine knee joint tissues (fibrous cartilage, hyaline cartilage, and bone) in saline was assessed as a function of radiant exposure (160-640 J/cm2), pulse width (150, 200, 250, 450usec, FWHM) and a repetition rate of 2Hz. The delivery system used consisted of a low-OH silica core/cladding diameters 400/440pm and 600/720pm, respectively. The laser fiber tip was held perpendicular to the tissue and weighted to exert a constant pressure of 40g/m2. The irradiated tissue sample6 were placed in formalin for subsequent histologic evaluation. The dimension of the thermal damage zone was evaluated by measurement of the damage area surrounding the craters with grid ruler eyepiece. All tissues used in this study could be efficiently ablated using two micron lasers (Table I & 11)." @default.
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- W2163280318 date "2005-08-24" @default.
- W2163280318 modified "2023-09-26" @default.
- W2163280318 title "Effects Of Pulsed Mid-infrared Lasers On Bovine Knee Joint Tissues" @default.
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- W2163280318 doi "https://doi.org/10.1109/leos.1992.694138" @default.
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