FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163382819> ?p ?o ?g. }

• W2163382819 endingPage "582" @default.
• W2163382819 startingPage "580" @default.
• W2163382819 abstract "Myostatin is an inhibitor of skeletal muscle growth. Disruption of the Mstn gene in mice results in muscles that weigh two to three times those of controls, but precisely how myostatin signals to exert its effects on muscle is unclear. We used the Affymetrix GeneChip system to identify differences in gene expression between myostatin null and wild-type mice. The results indicated a switch in muscle fiber type, from slow to fast, in the absence of myostatin. They also indicated that myostatin may act upstream of Wnt pathway components. Notably, it repressed expression of Wnt4. Wnt4 was capable of stimulating satellite cell proliferation, while inhibition of Wnt signaling down-regulated satellite cell proliferation. This evidence points to a role for Wnt/calcium signaling in the growth and maintenance of postnatal skeletal muscle. This study offers new insight into potential downstream targets of myostatin, which will be beneficial for elucidation of the mechanism through which myostatin acts to inhibit muscle growth." @default.
• W2163382819 created "2016-06-24" @default.
• W2163382819 creator A5047522477 @default.
• W2163382819 creator A5049836688 @default.
• W2163382819 creator A5062710121 @default.
• W2163382819 creator A5066910802 @default.
• W2163382819 date "2006-01-19" @default.
• W2163382819 modified "2023-10-17" @default.
• W2163382819 title "Transcriptional profiling of myostatin‐knockout mice implicates Wnt signaling in postnatal skeletal muscle growth and hypertrophy" @default.
• W2163382819 cites W137188978 @default.
• W2163382819 cites W1887141904 @default.
• W2163382819 cites W1930882462 @default.
• W2163382819 cites W1956572439 @default.
• W2163382819 cites W1967533362 @default.
• W2163382819 cites W1973516848 @default.
• W2163382819 cites W1974799396 @default.
• W2163382819 cites W1978039987 @default.
• W2163382819 cites W1978843299 @default.
• W2163382819 cites W1982010945 @default.
• W2163382819 cites W1982210644 @default.
• W2163382819 cites W1982709013 @default.
• W2163382819 cites W1982715073 @default.
• W2163382819 cites W1991162692 @default.
• W2163382819 cites W1991671544 @default.
• W2163382819 cites W1993677820 @default.
• W2163382819 cites W1999921847 @default.
• W2163382819 cites W2007043944 @default.
• W2163382819 cites W2011583521 @default.
• W2163382819 cites W2011982245 @default.
• W2163382819 cites W2015364457 @default.
• W2163382819 cites W2020053900 @default.
• W2163382819 cites W2025463260 @default.
• W2163382819 cites W2029143606 @default.
• W2163382819 cites W2029441111 @default.
• W2163382819 cites W2029855244 @default.
• W2163382819 cites W2038254381 @default.
• W2163382819 cites W2047603186 @default.
• W2163382819 cites W2048134135 @default.
• W2163382819 cites W2053079324 @default.
• W2163382819 cites W2061364925 @default.
• W2163382819 cites W2062578421 @default.
• W2163382819 cites W2064030316 @default.
• W2163382819 cites W2064537289 @default.
• W2163382819 cites W2064764081 @default.
• W2163382819 cites W2064895186 @default.
• W2163382819 cites W2073269248 @default.
• W2163382819 cites W2073479496 @default.
• W2163382819 cites W2080388787 @default.
• W2163382819 cites W2083215537 @default.
• W2163382819 cites W2087144973 @default.
• W2163382819 cites W2087803244 @default.
• W2163382819 cites W2092051076 @default.
• W2163382819 cites W2096713221 @default.
• W2163382819 cites W2098453858 @default.
• W2163382819 cites W2100345592 @default.
• W2163382819 cites W2104000274 @default.
• W2163382819 cites W2104204293 @default.
• W2163382819 cites W2104413464 @default.
• W2163382819 cites W2107277218 @default.
• W2163382819 cites W2110065044 @default.
• W2163382819 cites W2112015741 @default.
• W2163382819 cites W2117748303 @default.
• W2163382819 cites W2122059149 @default.
• W2163382819 cites W2122683221 @default.
• W2163382819 cites W2123039189 @default.
• W2163382819 cites W2124326407 @default.
• W2163382819 cites W2127280898 @default.
• W2163382819 cites W2127938920 @default.
• W2163382819 cites W2130122556 @default.
• W2163382819 cites W2136912907 @default.
• W2163382819 cites W2137181404 @default.
• W2163382819 cites W2137814808 @default.
• W2163382819 cites W2147257521 @default.
• W2163382819 cites W2149993139 @default.
• W2163382819 cites W2153289066 @default.
• W2163382819 cites W2154283964 @default.
• W2163382819 cites W2154568166 @default.
• W2163382819 cites W2160199212 @default.
• W2163382819 cites W2161073961 @default.
• W2163382819 cites W2162405663 @default.
• W2163382819 cites W2162866938 @default.
• W2163382819 cites W2165868509 @default.
• W2163382819 cites W2166877291 @default.
• W2163382819 cites W2167839803 @default.
• W2163382819 cites W2170582708 @default.
• W2163382819 cites W2171996338 @default.
• W2163382819 cites W2176966894 @default.
• W2163382819 cites W2184324819 @default.
• W2163382819 cites W2224822722 @default.
• W2163382819 cites W2302421723 @default.
• W2163382819 doi "https://doi.org/10.1096/fj.05-5125fje" @default.
• W2163382819 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16423875" @default.
• W2163382819 hasPublicationYear "2006" @default.
• W2163382819 type Work @default.
• W2163382819 sameAs 2163382819 @default.
• W2163382819 citedByCount "121" @default.
• W2163382819 countsByYear W21633828192012 @default.
• W2163382819 countsByYear W21633828192013 @default.

• next