FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163516165> ?p ?o ?g. }

• W2163516165 endingPage "706" @default.
• W2163516165 startingPage "702" @default.
• W2163516165 abstract "The contribution of centrally originating sympathetic activity to the myocardial extracellular accumulation of noradrenaline during the early phase of ischemia has been assessed in a perfused (Langendorff) rat heart preparation isolated except for its sympathetic innervation. A 10-minute electrical stimulation (4 Hz, 5 V) of the left cervicothoracic ganglion during normal perfusion causes the overflow of 177.5 +/- 13.7 pmol noradrenaline/g heart, whereas such stimulation during ischemia liberates only 21.5 +/- 3.6 pmol/g (collected during reperfusion). When neuronal reuptake is blocked by desipramine, corresponding values are 321.5 +/- 22.5 pmol/g (normal flow) and 151.8 +/- 22.4 pmol/g (ischemia). After combined blockade of neuronal uptake, extraneuronal uptake, and alpha 2-receptors, nerve stimulation liberates 674 +/- 22 pmol/g during normal flow and 206 +/- 24.3 pmol/g during ischemia. These results suggest that, in vivo, centrally originating neural activity would not lead to substantial accumulation of noradrenaline within the extracellular space of the ischemic myocardium. This failure of accumulation is due to both a functioning neuronal uptake of noradrenaline and a failure of neurotransmission." @default.
• W2163516165 created "2016-06-24" @default.
• W2163516165 creator A5025612299 @default.
• W2163516165 creator A5037320109 @default.
• W2163516165 creator A5051005374 @default.
• W2163516165 creator A5082586880 @default.
• W2163516165 creator A5090370545 @default.
• W2163516165 date "1984-11-01" @default.
• W2163516165 modified "2023-10-16" @default.
• W2163516165 title "Release of endogenous catecholamines in the ischemic myocardium of the rat. Part B: Effect of sympathetic nerve stimulation." @default.
• W2163516165 cites W1501685573 @default.
• W2163516165 cites W1972568795 @default.
• W2163516165 cites W1975200068 @default.
• W2163516165 cites W2022050836 @default.
• W2163516165 cites W2033168194 @default.
• W2163516165 cites W2058702212 @default.
• W2163516165 cites W2076636600 @default.
• W2163516165 cites W2079405986 @default.
• W2163516165 cites W2079713804 @default.
• W2163516165 cites W2081621943 @default.
• W2163516165 cites W2081793403 @default.
• W2163516165 cites W2092771620 @default.
• W2163516165 cites W2110076805 @default.
• W2163516165 cites W2131086816 @default.
• W2163516165 cites W2442246255 @default.
• W2163516165 doi "https://doi.org/10.1161/01.res.55.5.702" @default.
• W2163516165 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6488490" @default.
• W2163516165 hasPublicationYear "1984" @default.
• W2163516165 type Work @default.
• W2163516165 sameAs 2163516165 @default.
• W2163516165 citedByCount "73" @default.
• W2163516165 countsByYear W21635161652012 @default.
• W2163516165 countsByYear W21635161652015 @default.
• W2163516165 countsByYear W21635161652021 @default.
• W2163516165 countsByYear W21635161652022 @default.
• W2163516165 crossrefType "journal-article" @default.
• W2163516165 hasAuthorship W2163516165A5025612299 @default.
• W2163516165 hasAuthorship W2163516165A5037320109 @default.
• W2163516165 hasAuthorship W2163516165A5051005374 @default.
• W2163516165 hasAuthorship W2163516165A5082586880 @default.
• W2163516165 hasAuthorship W2163516165A5090370545 @default.
• W2163516165 hasBestOaLocation W21635161651 @default.
• W2163516165 hasConcept C126322002 @default.
• W2163516165 hasConcept C134018914 @default.
• W2163516165 hasConcept C146957229 @default.
• W2163516165 hasConcept C16613235 @default.
• W2163516165 hasConcept C170493617 @default.
• W2163516165 hasConcept C185592680 @default.
• W2163516165 hasConcept C200170125 @default.
• W2163516165 hasConcept C24998067 @default.
• W2163516165 hasConcept C2775864247 @default.
• W2163516165 hasConcept C2775894120 @default.
• W2163516165 hasConcept C2778514916 @default.
• W2163516165 hasConcept C2779177272 @default.
• W2163516165 hasConcept C2780250439 @default.
• W2163516165 hasConcept C2781161787 @default.
• W2163516165 hasConcept C28406088 @default.
• W2163516165 hasConcept C50156730 @default.
• W2163516165 hasConcept C513476851 @default.
• W2163516165 hasConcept C541997718 @default.
• W2163516165 hasConcept C55493867 @default.
• W2163516165 hasConcept C71924100 @default.
• W2163516165 hasConcept C99631742 @default.
• W2163516165 hasConceptScore W2163516165C126322002 @default.
• W2163516165 hasConceptScore W2163516165C134018914 @default.
• W2163516165 hasConceptScore W2163516165C146957229 @default.
• W2163516165 hasConceptScore W2163516165C16613235 @default.
• W2163516165 hasConceptScore W2163516165C170493617 @default.
• W2163516165 hasConceptScore W2163516165C185592680 @default.
• W2163516165 hasConceptScore W2163516165C200170125 @default.
• W2163516165 hasConceptScore W2163516165C24998067 @default.
• W2163516165 hasConceptScore W2163516165C2775864247 @default.
• W2163516165 hasConceptScore W2163516165C2775894120 @default.
• W2163516165 hasConceptScore W2163516165C2778514916 @default.
• W2163516165 hasConceptScore W2163516165C2779177272 @default.
• W2163516165 hasConceptScore W2163516165C2780250439 @default.
• W2163516165 hasConceptScore W2163516165C2781161787 @default.
• W2163516165 hasConceptScore W2163516165C28406088 @default.
• W2163516165 hasConceptScore W2163516165C50156730 @default.
• W2163516165 hasConceptScore W2163516165C513476851 @default.
• W2163516165 hasConceptScore W2163516165C541997718 @default.
• W2163516165 hasConceptScore W2163516165C55493867 @default.
• W2163516165 hasConceptScore W2163516165C71924100 @default.
• W2163516165 hasConceptScore W2163516165C99631742 @default.
• W2163516165 hasIssue "5" @default.
• W2163516165 hasLocation W21635161651 @default.
• W2163516165 hasLocation W21635161652 @default.
• W2163516165 hasOpenAccess W2163516165 @default.
• W2163516165 hasPrimaryLocation W21635161651 @default.
• W2163516165 hasRelatedWork W1982053398 @default.
• W2163516165 hasRelatedWork W1983422406 @default.
• W2163516165 hasRelatedWork W2009922975 @default.
• W2163516165 hasRelatedWork W2024007776 @default.
• W2163516165 hasRelatedWork W2044619770 @default.
• W2163516165 hasRelatedWork W2070996648 @default.
• W2163516165 hasRelatedWork W2071491126 @default.
• W2163516165 hasRelatedWork W2412814744 @default.
• W2163516165 hasRelatedWork W2422405004 @default.

• next