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- W2163526229 abstract "Three-dimensional structures are now known for roughly half of all protein families. It is thus quite likely, in searching sequence databases, that one will encounter a homolog with known structure and be able to use this information to infer structure-function properties. The goal of Entrez's 3D structure database is to make this information accessible and useful to molecular biologists. To this end, Entrez's search engine provides three powerful features: (i) Links between databases; one may search by term matching in Medline((R)), for example, and link to 3D structures reported in these articles. (ii) Sequence and structure neighbors; one may select all sequences similar to one of interest, for example, and link to any known 3D structures. (iii) Sequence and structure visualization; identifying a homolog with known structure, one may view a combined molecular-graphic and alignment display, to infer approximate 3D structure. Entrez's MMDB (Molecular Modeling DataBase) may be accessed at: http://www.ncbi.nlm.nih.gov/Entrez/structure.html" @default.
- W2163526229 created "2016-06-24" @default.
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- W2163526229 date "2000-01-01" @default.
- W2163526229 modified "2023-10-16" @default.
- W2163526229 title "MMDB: 3D structure data in Entrez" @default.
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- W2163526229 doi "https://doi.org/10.1093/nar/28.1.243" @default.
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