Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163540965> ?p ?o ?g. }
- W2163540965 endingPage "7" @default.
- W2163540965 startingPage "673" @default.
- W2163540965 abstract "The management of intractable epilepsy in children and adults is challenging. For patients who do not respond to anti-epileptic drugs and are not suitable candidates for epilepsy surgery, vagal nerve stimulation (VNS) is a viable alternative for reducing seizure frequency.In this retrospective multicenter open-label study we examined the efficacy and tolerability of VNS in patients in five adult and pediatric epilepsy centers in Israel. All patients had drug-resistant epilepsy and after VNS implantation in 2006-2007 were followed for a minimum of 18 months. Patients were divided into two age groups: < 21 and > 21 years old.Fifty-six adults and children had a stimulator implanted in 2006-2007. At 18 months post-VNS implantation, none of the patients was seizure-free, 24.3% reported a reduction in seizures of > or = 75%, 19% reported a 50-75% reduction, and 10.8% a 25-50% reduction. The best response rate occurred in patients with complex partial seizures. Among these patients, 7 reported a > or = 75% reduction, 5 patients a 50-75% reduction, 3 patients a 25-50% reduction, and 8 patients a < 25% reduction. A comparison of the two age groups showed that the older group (< 21 years old) had fewer seizures than the younger group.VNS is a relatively effective and safe palliative method for treating refractory epilepsy in both adults and children. It is an alternative treatment for patients with drug-resistant epilepsy, even after a relatively long disease duration, who are not candidates for localized epilepsy surgery." @default.
- W2163540965 created "2016-06-24" @default.
- W2163540965 creator A5002728024 @default.
- W2163540965 creator A5013222299 @default.
- W2163540965 creator A5014806917 @default.
- W2163540965 creator A5030011479 @default.
- W2163540965 creator A5036220371 @default.
- W2163540965 creator A5048611020 @default.
- W2163540965 creator A5060190811 @default.
- W2163540965 creator A5069496038 @default.
- W2163540965 creator A5079817761 @default.
- W2163540965 creator A5086051318 @default.
- W2163540965 date "2013-11-01" @default.
- W2163540965 modified "2023-10-16" @default.
- W2163540965 title "The Israeli retrospective multicenter open-label study evaluating vagus nerve stimulation efficacy in children and adults." @default.
- W2163540965 cites W1561389266 @default.
- W2163540965 cites W1912685757 @default.
- W2163540965 cites W1980644444 @default.
- W2163540965 cites W1983022057 @default.
- W2163540965 cites W1987078313 @default.
- W2163540965 cites W1987692182 @default.
- W2163540965 cites W1993874893 @default.
- W2163540965 cites W2017623698 @default.
- W2163540965 cites W2018368033 @default.
- W2163540965 cites W2022305238 @default.
- W2163540965 cites W2028388181 @default.
- W2163540965 cites W2028701220 @default.
- W2163540965 cites W2035978392 @default.
- W2163540965 cites W2038561889 @default.
- W2163540965 cites W2050586703 @default.
- W2163540965 cites W2053283813 @default.
- W2163540965 cites W2056338994 @default.
- W2163540965 cites W2070021096 @default.
- W2163540965 cites W2080329143 @default.
- W2163540965 cites W2086407120 @default.
- W2163540965 cites W2097002694 @default.
- W2163540965 cites W2101808151 @default.
- W2163540965 cites W2120163169 @default.
- W2163540965 cites W2154080699 @default.
- W2163540965 cites W579834933 @default.
- W2163540965 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24511646" @default.
- W2163540965 hasPublicationYear "2013" @default.
- W2163540965 type Work @default.
- W2163540965 sameAs 2163540965 @default.
- W2163540965 citedByCount "8" @default.
- W2163540965 countsByYear W21635409652013 @default.
- W2163540965 countsByYear W21635409652014 @default.
- W2163540965 countsByYear W21635409652016 @default.
- W2163540965 countsByYear W21635409652017 @default.
- W2163540965 countsByYear W21635409652020 @default.
- W2163540965 crossrefType "journal-article" @default.
- W2163540965 hasAuthorship W2163540965A5002728024 @default.
- W2163540965 hasAuthorship W2163540965A5013222299 @default.
- W2163540965 hasAuthorship W2163540965A5014806917 @default.
- W2163540965 hasAuthorship W2163540965A5030011479 @default.
- W2163540965 hasAuthorship W2163540965A5036220371 @default.
- W2163540965 hasAuthorship W2163540965A5048611020 @default.
- W2163540965 hasAuthorship W2163540965A5060190811 @default.
- W2163540965 hasAuthorship W2163540965A5069496038 @default.
- W2163540965 hasAuthorship W2163540965A5079817761 @default.
- W2163540965 hasAuthorship W2163540965A5086051318 @default.
- W2163540965 hasConcept C118552586 @default.
- W2163540965 hasConcept C126322002 @default.
- W2163540965 hasConcept C141071460 @default.
- W2163540965 hasConcept C167135981 @default.
- W2163540965 hasConcept C187212893 @default.
- W2163540965 hasConcept C197934379 @default.
- W2163540965 hasConcept C205545832 @default.
- W2163540965 hasConcept C24998067 @default.
- W2163540965 hasConcept C2778186239 @default.
- W2163540965 hasConcept C2778375690 @default.
- W2163540965 hasConcept C2779307984 @default.
- W2163540965 hasConcept C2780087125 @default.
- W2163540965 hasConcept C2780803581 @default.
- W2163540965 hasConcept C2781404750 @default.
- W2163540965 hasConcept C2910833928 @default.
- W2163540965 hasConcept C42219234 @default.
- W2163540965 hasConcept C71924100 @default.
- W2163540965 hasConceptScore W2163540965C118552586 @default.
- W2163540965 hasConceptScore W2163540965C126322002 @default.
- W2163540965 hasConceptScore W2163540965C141071460 @default.
- W2163540965 hasConceptScore W2163540965C167135981 @default.
- W2163540965 hasConceptScore W2163540965C187212893 @default.
- W2163540965 hasConceptScore W2163540965C197934379 @default.
- W2163540965 hasConceptScore W2163540965C205545832 @default.
- W2163540965 hasConceptScore W2163540965C24998067 @default.
- W2163540965 hasConceptScore W2163540965C2778186239 @default.
- W2163540965 hasConceptScore W2163540965C2778375690 @default.
- W2163540965 hasConceptScore W2163540965C2779307984 @default.
- W2163540965 hasConceptScore W2163540965C2780087125 @default.
- W2163540965 hasConceptScore W2163540965C2780803581 @default.
- W2163540965 hasConceptScore W2163540965C2781404750 @default.
- W2163540965 hasConceptScore W2163540965C2910833928 @default.
- W2163540965 hasConceptScore W2163540965C42219234 @default.
- W2163540965 hasConceptScore W2163540965C71924100 @default.
- W2163540965 hasIssue "11" @default.
- W2163540965 hasLocation W21635409651 @default.
- W2163540965 hasOpenAccess W2163540965 @default.