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- W2163595408 abstract "Proteasomes have recently been shown to be central to the production of antigenic peptides that can bind to major histocompatibility complex class I molecules. Here, Marcus Groettrup and colleagues discuss the structural architecture of the proteasome and its proteolytic mechanisms with respect to the generation of antigenic peptides. They suggest that exchanges of proteolytic proteasome subunits and proteasome activators cooperate to optimize the production of antigens for cytotoxic T cells." @default.
- W2163595408 created "2016-06-24" @default.
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- W2163595408 date "1996-09-01" @default.
- W2163595408 modified "2023-09-30" @default.
- W2163595408 title "Peptide antigen production by the proteasome: complexity provides efficiency" @default.
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- W2163595408 doi "https://doi.org/10.1016/0167-5699(96)10051-7" @default.
- W2163595408 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8854562" @default.
- W2163595408 hasPublicationYear "1996" @default.
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