FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163622408> ?p ?o ?g. }

• W2163622408 endingPage "677" @default.
• W2163622408 startingPage "670" @default.
• W2163622408 abstract "Tumor-infiltrating lymphocytes (TILs) and forkhead box transcription factor positive (FoxP3(+)) regulatory T-lymphocytes (TREGs) have been analyzed in a variety of tumors but not in oesophageal adenocarcinoma.Tissue from 130 adenocarcinomas of the oesophagus was re-evaluated in the centre and periphery of tumour, respectively, using immunohistochemical staining with anti-CD3, anti-CD4, anti-CD8, anti-CD25 and anti-FoxP3 antibodies. Patients were stratified according neoadjuvant treatment. 106 patients proceeded directly to surgery and 24 underwent pre-operative radio-chemotherapy (RCT).In patients without RCT, TILs were found significantly more frequently in the periphery with the exception of CD25(+) cells. Patients with centrally low counts of FoxP3(+) TREGs had higher tumour stages than patients with high counts (p < 0.011). The number of FoxP3(+) TREGs was significantly associated with the number of CD8(+) cells (centre: p < 0.001, periphery: p = 0.002). The multivariate regression analysis identified UICC stage (IIB/III vs. I/IIA, hazard ratio 2.6, p = 0.011) and completeness of resection (no vs. yes, hazard ratio 2.3, p = 0.015) as independent predictors of survival. RCT significantly reduced the number of TREGs in the centre (p = 0.016) but not the number of the other TILs.UICC stage and completeness of resection but none of the TILs were prognostic markers for long-term survival. We found no morphologic evidence that TREGs suppress immunological response, represented by the infiltration of CD8(+) cells. Preoperative RCT affected the centre of tumours more than the periphery, which may indicate that it does not inhibit the host-to-tumour reaction. RCT affects TREGs more than the other TILs." @default.
• W2163622408 created "2016-06-24" @default.
• W2163622408 creator A5008894098 @default.
• W2163622408 creator A5010957597 @default.
• W2163622408 creator A5029902719 @default.
• W2163622408 creator A5057172500 @default.
• W2163622408 creator A5062617194 @default.
• W2163622408 creator A5090576893 @default.
• W2163622408 creator A5091441095 @default.
• W2163622408 date "2010-07-01" @default.
• W2163622408 modified "2023-09-25" @default.
• W2163622408 title "Tumour-infiltrating lymphocytes and survival in patients with adenocarcinoma of the oesophagus" @default.
• W2163622408 cites W1522859339 @default.
• W2163622408 cites W1530044612 @default.
• W2163622408 cites W1865426939 @default.
• W2163622408 cites W1977468182 @default.
• W2163622408 cites W1994850185 @default.
• W2163622408 cites W1996858090 @default.
• W2163622408 cites W1998350666 @default.
• W2163622408 cites W2000170004 @default.
• W2163622408 cites W2022056254 @default.
• W2163622408 cites W2023134457 @default.
• W2163622408 cites W2040594411 @default.
• W2163622408 cites W2052493633 @default.
• W2163622408 cites W2072347154 @default.
• W2163622408 cites W2079548788 @default.
• W2163622408 cites W2091387892 @default.
• W2163622408 cites W2091990387 @default.
• W2163622408 cites W2097811455 @default.
• W2163622408 cites W2105459360 @default.
• W2163622408 cites W2113217158 @default.
• W2163622408 cites W2135398071 @default.
• W2163622408 cites W2137074525 @default.
• W2163622408 cites W2142300779 @default.
• W2163622408 cites W2146898402 @default.
• W2163622408 cites W2150678612 @default.
• W2163622408 cites W2151444514 @default.
• W2163622408 cites W2157620815 @default.
• W2163622408 cites W2171775292 @default.
• W2163622408 doi "https://doi.org/10.1016/j.ejso.2010.05.012" @default.
• W2163622408 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20510571" @default.
• W2163622408 hasPublicationYear "2010" @default.
• W2163622408 type Work @default.
• W2163622408 sameAs 2163622408 @default.
• W2163622408 citedByCount "56" @default.
• W2163622408 countsByYear W21636224082012 @default.
• W2163622408 countsByYear W21636224082013 @default.
• W2163622408 countsByYear W21636224082014 @default.
• W2163622408 countsByYear W21636224082015 @default.
• W2163622408 countsByYear W21636224082016 @default.
• W2163622408 countsByYear W21636224082017 @default.
• W2163622408 countsByYear W21636224082018 @default.
• W2163622408 countsByYear W21636224082019 @default.
• W2163622408 countsByYear W21636224082020 @default.
• W2163622408 countsByYear W21636224082021 @default.
• W2163622408 countsByYear W21636224082022 @default.
• W2163622408 countsByYear W21636224082023 @default.
• W2163622408 crossrefType "journal-article" @default.
• W2163622408 hasAuthorship W2163622408A5008894098 @default.
• W2163622408 hasAuthorship W2163622408A5010957597 @default.
• W2163622408 hasAuthorship W2163622408A5029902719 @default.
• W2163622408 hasAuthorship W2163622408A5057172500 @default.
• W2163622408 hasAuthorship W2163622408A5062617194 @default.
• W2163622408 hasAuthorship W2163622408A5090576893 @default.
• W2163622408 hasAuthorship W2163622408A5091441095 @default.
• W2163622408 hasConcept C121608353 @default.
• W2163622408 hasConcept C126322002 @default.
• W2163622408 hasConcept C142724271 @default.
• W2163622408 hasConcept C143998085 @default.
• W2163622408 hasConcept C146357865 @default.
• W2163622408 hasConcept C151730666 @default.
• W2163622408 hasConcept C167672396 @default.
• W2163622408 hasConcept C203014093 @default.
• W2163622408 hasConcept C204232928 @default.
• W2163622408 hasConcept C207103383 @default.
• W2163622408 hasConcept C2778326572 @default.
• W2163622408 hasConcept C2779727006 @default.
• W2163622408 hasConcept C2780091936 @default.
• W2163622408 hasConcept C2781182431 @default.
• W2163622408 hasConcept C44249647 @default.
• W2163622408 hasConcept C71924100 @default.
• W2163622408 hasConcept C86803240 @default.
• W2163622408 hasConcept C8891405 @default.
• W2163622408 hasConcept C90924648 @default.
• W2163622408 hasConceptScore W2163622408C121608353 @default.
• W2163622408 hasConceptScore W2163622408C126322002 @default.
• W2163622408 hasConceptScore W2163622408C142724271 @default.
• W2163622408 hasConceptScore W2163622408C143998085 @default.
• W2163622408 hasConceptScore W2163622408C146357865 @default.
• W2163622408 hasConceptScore W2163622408C151730666 @default.
• W2163622408 hasConceptScore W2163622408C167672396 @default.
• W2163622408 hasConceptScore W2163622408C203014093 @default.
• W2163622408 hasConceptScore W2163622408C204232928 @default.
• W2163622408 hasConceptScore W2163622408C207103383 @default.
• W2163622408 hasConceptScore W2163622408C2778326572 @default.
• W2163622408 hasConceptScore W2163622408C2779727006 @default.
• W2163622408 hasConceptScore W2163622408C2780091936 @default.
• W2163622408 hasConceptScore W2163622408C2781182431 @default.

• next