FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163629116> ?p ?o ?g. }

• W2163629116 endingPage "1475" @default.
• W2163629116 startingPage "1469" @default.
• W2163629116 abstract "Objectives: Published series on the synchronous combined resection of brain metastases and primary non-small cell lung cancer are small and scarce. We therefore undertook a multicenter retrospective study to determine long-term survival and identify potential prognostic factors. Design: Our series includes 103 patients who were operated on between 1985 and 1998 for the following tumors: adenocarcinomas (74); squamous cell carcinomas (20); and large cell carcinomas (9). Three patients had two brain metastases, and one patient had three metastases; the remaining patients had a single metastasis. Ninety-three patients presented with neurologic signs that regressed completely after resection in 60 patients and partially, in 26 patients. Neurosurgical resection was incomplete in six patients. Seventy-five patients received postoperative brain radiotherapy. The time interval between the brain operation and the lung resection was < 4 months. Pulmonary resection was incomplete in eight patients. Results: The survival calculated from the date of the first operation was 56% at 1 year, 28% at 2 years, and 11% at 5 years. Univariate analysis showed a better prognosis for adenocarcinomas (p = 0.019) and a trend toward a better prognosis for patients with small pulmonary tumors (T1 vs T3, p = 0.068), N0 stage disease (N0 vs N+, p = 0.069), and complete pulmonary resection (p = 0.057). In a multivariate analysis, adenocarcinoma histology also affected the survival rate (p = 0.03). Conclusions: It seems legitimate to proceed with lung resection after complete resection of a single brain metastasis, at least in patients with an adenocarcinoma and a small lung tumor and without abnormal mediastinal lymph nodes seen on the CT scan or during mediastinoscopy. Published series on the synchronous combined resection of brain metastases and primary non-small cell lung cancer are small and scarce. We therefore undertook a multicenter retrospective study to determine long-term survival and identify potential prognostic factors. Our series includes 103 patients who were operated on between 1985 and 1998 for the following tumors: adenocarcinomas (74); squamous cell carcinomas (20); and large cell carcinomas (9). Three patients had two brain metastases, and one patient had three metastases; the remaining patients had a single metastasis. Ninety-three patients presented with neurologic signs that regressed completely after resection in 60 patients and partially, in 26 patients. Neurosurgical resection was incomplete in six patients. Seventy-five patients received postoperative brain radiotherapy. The time interval between the brain operation and the lung resection was < 4 months. Pulmonary resection was incomplete in eight patients. The survival calculated from the date of the first operation was 56% at 1 year, 28% at 2 years, and 11% at 5 years. Univariate analysis showed a better prognosis for adenocarcinomas (p = 0.019) and a trend toward a better prognosis for patients with small pulmonary tumors (T1 vs T3, p = 0.068), N0 stage disease (N0 vs N+, p = 0.069), and complete pulmonary resection (p = 0.057). In a multivariate analysis, adenocarcinoma histology also affected the survival rate (p = 0.03). It seems legitimate to proceed with lung resection after complete resection of a single brain metastasis, at least in patients with an adenocarcinoma and a small lung tumor and without abnormal mediastinal lymph nodes seen on the CT scan or during mediastinoscopy." @default.
• W2163629116 created "2016-06-24" @default.
• W2163629116 creator A5008255065 @default.
• W2163629116 creator A5011012519 @default.
• W2163629116 creator A5024546088 @default.
• W2163629116 creator A5040640740 @default.
• W2163629116 creator A5078878520 @default.
• W2163629116 creator A5078976562 @default.
• W2163629116 creator A5089401140 @default.
• W2163629116 date "2001-05-01" @default.
• W2163629116 modified "2023-10-18" @default.
• W2163629116 title "Surgical Management of Non-small Cell Lung Cancer With Synchronous Brain Metastases" @default.
• W2163629116 cites W1514077574 @default.
• W2163629116 cites W1919092210 @default.
• W2163629116 cites W1985799717 @default.
• W2163629116 cites W1986066043 @default.
• W2163629116 cites W1996187562 @default.
• W2163629116 cites W2003917401 @default.
• W2163629116 cites W2004852620 @default.
• W2163629116 cites W2010128411 @default.
• W2163629116 cites W2038252730 @default.
• W2163629116 cites W2057331329 @default.
• W2163629116 cites W2065834230 @default.
• W2163629116 cites W2077722214 @default.
• W2163629116 cites W2109523793 @default.
• W2163629116 cites W2125793053 @default.
• W2163629116 cites W2329793926 @default.
• W2163629116 cites W2464537647 @default.
• W2163629116 cites W2766048157 @default.
• W2163629116 cites W4293241248 @default.
• W2163629116 cites W4293363005 @default.
• W2163629116 doi "https://doi.org/10.1378/chest.119.5.1469" @default.
• W2163629116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11348955" @default.
• W2163629116 hasPublicationYear "2001" @default.
• W2163629116 type Work @default.
• W2163629116 sameAs 2163629116 @default.
• W2163629116 citedByCount "176" @default.
• W2163629116 countsByYear W21636291162012 @default.
• W2163629116 countsByYear W21636291162013 @default.
• W2163629116 countsByYear W21636291162014 @default.
• W2163629116 countsByYear W21636291162015 @default.
• W2163629116 countsByYear W21636291162016 @default.
• W2163629116 countsByYear W21636291162017 @default.
• W2163629116 countsByYear W21636291162018 @default.
• W2163629116 countsByYear W21636291162019 @default.
• W2163629116 countsByYear W21636291162020 @default.
• W2163629116 countsByYear W21636291162021 @default.
• W2163629116 countsByYear W21636291162022 @default.
• W2163629116 countsByYear W21636291162023 @default.
• W2163629116 crossrefType "journal-article" @default.
• W2163629116 hasAuthorship W2163629116A5008255065 @default.
• W2163629116 hasAuthorship W2163629116A5011012519 @default.
• W2163629116 hasAuthorship W2163629116A5024546088 @default.
• W2163629116 hasAuthorship W2163629116A5040640740 @default.
• W2163629116 hasAuthorship W2163629116A5078878520 @default.
• W2163629116 hasAuthorship W2163629116A5078976562 @default.
• W2163629116 hasAuthorship W2163629116A5089401140 @default.
• W2163629116 hasConcept C121608353 @default.
• W2163629116 hasConcept C126322002 @default.
• W2163629116 hasConcept C126838900 @default.
• W2163629116 hasConcept C141071460 @default.
• W2163629116 hasConcept C143998085 @default.
• W2163629116 hasConcept C144301174 @default.
• W2163629116 hasConcept C146357865 @default.
• W2163629116 hasConcept C151730666 @default.
• W2163629116 hasConcept C2776256026 @default.
• W2163629116 hasConcept C2777714996 @default.
• W2163629116 hasConcept C2778164965 @default.
• W2163629116 hasConcept C2779013556 @default.
• W2163629116 hasConcept C2781182431 @default.
• W2163629116 hasConcept C38180746 @default.
• W2163629116 hasConcept C509974204 @default.
• W2163629116 hasConcept C71924100 @default.
• W2163629116 hasConcept C86803240 @default.
• W2163629116 hasConceptScore W2163629116C121608353 @default.
• W2163629116 hasConceptScore W2163629116C126322002 @default.
• W2163629116 hasConceptScore W2163629116C126838900 @default.
• W2163629116 hasConceptScore W2163629116C141071460 @default.
• W2163629116 hasConceptScore W2163629116C143998085 @default.
• W2163629116 hasConceptScore W2163629116C144301174 @default.
• W2163629116 hasConceptScore W2163629116C146357865 @default.
• W2163629116 hasConceptScore W2163629116C151730666 @default.
• W2163629116 hasConceptScore W2163629116C2776256026 @default.
• W2163629116 hasConceptScore W2163629116C2777714996 @default.
• W2163629116 hasConceptScore W2163629116C2778164965 @default.
• W2163629116 hasConceptScore W2163629116C2779013556 @default.
• W2163629116 hasConceptScore W2163629116C2781182431 @default.
• W2163629116 hasConceptScore W2163629116C38180746 @default.
• W2163629116 hasConceptScore W2163629116C509974204 @default.
• W2163629116 hasConceptScore W2163629116C71924100 @default.
• W2163629116 hasConceptScore W2163629116C86803240 @default.
• W2163629116 hasIssue "5" @default.
• W2163629116 hasLocation W21636291161 @default.
• W2163629116 hasLocation W21636291162 @default.
• W2163629116 hasOpenAccess W2163629116 @default.
• W2163629116 hasPrimaryLocation W21636291161 @default.
• W2163629116 hasRelatedWork W1602357875 @default.
• W2163629116 hasRelatedWork W1831765636 @default.

• next