FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163635350> ?p ?o ?g. }

• W2163635350 endingPage "436" @default.
• W2163635350 startingPage "423" @default.
• W2163635350 abstract "Metamorphosis of amphibians requires reconfiguration of sensory and locomotor neural networks. In view of such plastic changes and implications of nitric oxide (NO) in neural developmental shaping, we examined via histochemistry and immunohistochemistry its synthetic enzyme nitric oxide synthase (NOS) in dorsal root ganglia (DRGs) and dorsal horn of the developing and adult frog Rana esculenta. In limb DRGs, NOS positivity was first and selectively detected just before limb bud appearance, increased during metamorphosis, and was then down-regulated. In adulthood, NOS was expressed in some DRG neurons at all segmental levels. Similar features were detected in the dorsal horn neuropil. In limb DRGs, cell counts in Nissl-stained sections revealed a twofold increase of differentiated neurons during metamorphosis and an additional twofold increase in adulthood. Perikaryal sizes in limb DRGs did not vary during metamorphosis but increased and were more heterogeneous in the adult frog, probably reflecting adaptation to body size. NOS and cell changes during metamorphosis were much less marked in DRGs at other levels. Carbocyanine tracing documented selective labeling of NOS-expressing hindlimb DRG neurons from the spinal nerve at the time of initiation of hindlimb movements. The findings show that, in limb DRG neurons, NOS parallels cell differentiation and limb development during metamorphosis. The data also provide evidence of NOS expression in DRG cells innervating the hindlimbs when sensorimotor circuits become functionally mature. This study indicates a key role of NO production in the maturation of sensory functions that subserves in amphibians the transition from swimming to tetrapod locomotion." @default.
• W2163635350 created "2016-06-24" @default.
• W2163635350 creator A5005708410 @default.
• W2163635350 creator A5029265169 @default.
• W2163635350 creator A5036090830 @default.
• W2163635350 creator A5064505785 @default.
• W2163635350 date "2004-03-29" @default.
• W2163635350 modified "2023-10-14" @default.
• W2163635350 title "Nitric oxide synthase expression and cell changes in dorsal root ganglia and spinal dorsal horn of developing and adultRana esculenta indicate a role of nitric oxide in limb metamorphosis" @default.
• W2163635350 cites W1565992048 @default.
• W2163635350 cites W1598492683 @default.
• W2163635350 cites W1647008873 @default.
• W2163635350 cites W1828866226 @default.
• W2163635350 cites W1968172431 @default.
• W2163635350 cites W1969574237 @default.
• W2163635350 cites W1976250274 @default.
• W2163635350 cites W1987850462 @default.
• W2163635350 cites W1994391769 @default.
• W2163635350 cites W1994473405 @default.
• W2163635350 cites W1996333267 @default.
• W2163635350 cites W1997806462 @default.
• W2163635350 cites W1997893768 @default.
• W2163635350 cites W2000200151 @default.
• W2163635350 cites W2000369189 @default.
• W2163635350 cites W2008606144 @default.
• W2163635350 cites W2015354238 @default.
• W2163635350 cites W2027329726 @default.
• W2163635350 cites W2032321830 @default.
• W2163635350 cites W2034565441 @default.
• W2163635350 cites W2037695927 @default.
• W2163635350 cites W2041069574 @default.
• W2163635350 cites W2050024990 @default.
• W2163635350 cites W2061598848 @default.
• W2163635350 cites W2063016781 @default.
• W2163635350 cites W2067457303 @default.
• W2163635350 cites W2067603890 @default.
• W2163635350 cites W2068133415 @default.
• W2163635350 cites W2068720114 @default.
• W2163635350 cites W2090613676 @default.
• W2163635350 cites W2091103803 @default.
• W2163635350 cites W2105580040 @default.
• W2163635350 cites W2121094130 @default.
• W2163635350 cites W2132397202 @default.
• W2163635350 cites W2135132703 @default.
• W2163635350 cites W2140799407 @default.
• W2163635350 cites W2147944067 @default.
• W2163635350 cites W2148821694 @default.
• W2163635350 cites W2198634537 @default.
• W2163635350 cites W2261984101 @default.
• W2163635350 cites W4243988437 @default.
• W2163635350 doi "https://doi.org/10.1002/cne.20057" @default.
• W2163635350 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15065117" @default.
• W2163635350 hasPublicationYear "2004" @default.
• W2163635350 type Work @default.
• W2163635350 sameAs 2163635350 @default.
• W2163635350 citedByCount "14" @default.
• W2163635350 countsByYear W21636353502013 @default.
• W2163635350 countsByYear W21636353502017 @default.
• W2163635350 countsByYear W21636353502023 @default.
• W2163635350 crossrefType "journal-article" @default.
• W2163635350 hasAuthorship W2163635350A5005708410 @default.
• W2163635350 hasAuthorship W2163635350A5029265169 @default.
• W2163635350 hasAuthorship W2163635350A5036090830 @default.
• W2163635350 hasAuthorship W2163635350A5064505785 @default.
• W2163635350 hasConcept C105702510 @default.
• W2163635350 hasConcept C134018914 @default.
• W2163635350 hasConcept C136397037 @default.
• W2163635350 hasConcept C169760540 @default.
• W2163635350 hasConcept C173758957 @default.
• W2163635350 hasConcept C2777622882 @default.
• W2163635350 hasConcept C2777831001 @default.
• W2163635350 hasConcept C2780775167 @default.
• W2163635350 hasConcept C51738704 @default.
• W2163635350 hasConcept C519581460 @default.
• W2163635350 hasConcept C529278444 @default.
• W2163635350 hasConcept C59822182 @default.
• W2163635350 hasConcept C86803240 @default.
• W2163635350 hasConceptScore W2163635350C105702510 @default.
• W2163635350 hasConceptScore W2163635350C134018914 @default.
• W2163635350 hasConceptScore W2163635350C136397037 @default.
• W2163635350 hasConceptScore W2163635350C169760540 @default.
• W2163635350 hasConceptScore W2163635350C173758957 @default.
• W2163635350 hasConceptScore W2163635350C2777622882 @default.
• W2163635350 hasConceptScore W2163635350C2777831001 @default.
• W2163635350 hasConceptScore W2163635350C2780775167 @default.
• W2163635350 hasConceptScore W2163635350C51738704 @default.
• W2163635350 hasConceptScore W2163635350C519581460 @default.
• W2163635350 hasConceptScore W2163635350C529278444 @default.
• W2163635350 hasConceptScore W2163635350C59822182 @default.
• W2163635350 hasConceptScore W2163635350C86803240 @default.
• W2163635350 hasIssue "4" @default.
• W2163635350 hasLocation W21636353501 @default.
• W2163635350 hasLocation W21636353502 @default.
• W2163635350 hasOpenAccess W2163635350 @default.
• W2163635350 hasPrimaryLocation W21636353501 @default.
• W2163635350 hasRelatedWork W1964132524 @default.
• W2163635350 hasRelatedWork W1967582304 @default.
• W2163635350 hasRelatedWork W2002861099 @default.

• next