FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163749351> ?p ?o ?g. }

• W2163749351 endingPage "127" @default.
• W2163749351 startingPage "121" @default.
• W2163749351 abstract "Abstract The advent of fast scintillators yielding great light yield and/or stopping power, along with advances in photomultiplier tubes and electronics, have rekindled interest in time-of-flight (TOF) PET. Because the potential performance improvements offered by TOF PET are substantial, efforts to improve PET timing should prove very fruitful. In this study, we performed Monte Carlo simulations to explore what gains in PET performance could be achieved if the coincidence resolving time (CRT) in the LYSO-based PET component of Discovery RX PET/CT scanner were improved. For this purpose, the GATE Monte Carlo package was utilized, providing the ability to model and characterize various physical phenomena in PET imaging. For the present investigation, count rate performance and signal to noise ratio (SNR) values in different activity concentrations were simulated for different coincidence timing windows of 4, 5.85, 6, 6.5, 8, 10 and 12 ns and with different CRTs of 100–900 ps FWHM involving 50 ps FWHM increments using the NEMA scatter phantom. Strong evidence supporting robustness of the simulations was found as observed in the good agreement between measured and simulated data for the cases of estimating axial sensitivity, axial and transaxial detection position, gamma non-collinearity angle distribution and positron annihilation distance. In the non-TOF context, the results show that the random event rate can be reduced by using narrower coincidence timing window widths, demonstrating considerable enhancements in the peak noise equivalent count rate (NECR) performance. The peak NECR had increased by ∼50% when utilizing the coincidence window width of 4 ns. At the same time, utilization of TOF information resulted in improved NECR and SNR with the dramatic reduction of random coincidences as a function of CRT. For example, with CRT of 500 ps FWHM, a factor of 2.3 reduction in random rates, factor of 1.5 increase in NECR and factor of 2.1 improvement in SNR is achievable. The results of this study show that in addition to the high sensitivity of Discovery RX PET/CT scanner, the implementation of TOF with proper CRT can efficiently improve the image quality in this scanner. Having successfully simulated the DRX scanner and utilization of TOF information, our research goal is to use the Monte Carlo simulation technique to arrive at powerful, accurate and feasible reconstruction algorithms." @default.
• W2163749351 created "2016-06-24" @default.
• W2163749351 creator A5001004234 @default.
• W2163749351 creator A5001211384 @default.
• W2163749351 creator A5002606129 @default.
• W2163749351 creator A5021438906 @default.
• W2163749351 creator A5036586704 @default.
• W2163749351 creator A5066026023 @default.
• W2163749351 date "2011-06-01" @default.
• W2163749351 modified "2023-09-30" @default.
• W2163749351 title "Investigation of time-of-flight benefits in an LYSO-based PET/CT scanner: A Monte Carlo study using GATE" @default.
• W2163749351 cites W1970952498 @default.
• W2163749351 cites W1976285425 @default.
• W2163749351 cites W1988051839 @default.
• W2163749351 cites W1993388378 @default.
• W2163749351 cites W2003597177 @default.
• W2163749351 cites W2012891375 @default.
• W2163749351 cites W2044838925 @default.
• W2163749351 cites W2049506340 @default.
• W2163749351 cites W2052531309 @default.
• W2163749351 cites W2056845218 @default.
• W2163749351 cites W2059842805 @default.
• W2163749351 cites W2103707010 @default.
• W2163749351 cites W2115304180 @default.
• W2163749351 cites W2116085429 @default.
• W2163749351 cites W2120555115 @default.
• W2163749351 cites W2123572206 @default.
• W2163749351 cites W2130040053 @default.
• W2163749351 cites W2135848264 @default.
• W2163749351 cites W2151969366 @default.
• W2163749351 cites W2152076753 @default.
• W2163749351 cites W2154743867 @default.
• W2163749351 cites W2158492906 @default.
• W2163749351 cites W2163610344 @default.
• W2163749351 cites W2167040277 @default.
• W2163749351 cites W2171091999 @default.
• W2163749351 cites W2179238185 @default.
• W2163749351 doi "https://doi.org/10.1016/j.nima.2011.03.030" @default.
• W2163749351 hasPublicationYear "2011" @default.
• W2163749351 type Work @default.
• W2163749351 sameAs 2163749351 @default.
• W2163749351 citedByCount "12" @default.
• W2163749351 countsByYear W21637493512013 @default.
• W2163749351 countsByYear W21637493512015 @default.
• W2163749351 countsByYear W21637493512017 @default.
• W2163749351 countsByYear W21637493512019 @default.
• W2163749351 countsByYear W21637493512020 @default.
• W2163749351 countsByYear W21637493512021 @default.
• W2163749351 crossrefType "journal-article" @default.
• W2163749351 hasAuthorship W2163749351A5001004234 @default.
• W2163749351 hasAuthorship W2163749351A5001211384 @default.
• W2163749351 hasAuthorship W2163749351A5002606129 @default.
• W2163749351 hasAuthorship W2163749351A5021438906 @default.
• W2163749351 hasAuthorship W2163749351A5036586704 @default.
• W2163749351 hasAuthorship W2163749351A5066026023 @default.
• W2163749351 hasConcept C105795698 @default.
• W2163749351 hasConcept C116915560 @default.
• W2163749351 hasConcept C120665830 @default.
• W2163749351 hasConcept C121332964 @default.
• W2163749351 hasConcept C127413603 @default.
• W2163749351 hasConcept C161694136 @default.
• W2163749351 hasConcept C185544564 @default.
• W2163749351 hasConcept C192562407 @default.
• W2163749351 hasConcept C19499675 @default.
• W2163749351 hasConcept C2779751349 @default.
• W2163749351 hasConcept C2780330291 @default.
• W2163749351 hasConcept C2989005 @default.
• W2163749351 hasConcept C33923547 @default.
• W2163749351 hasConcept C39432304 @default.
• W2163749351 hasConcept C41008148 @default.
• W2163749351 hasConcept C71924100 @default.
• W2163749351 hasConcept C94915269 @default.
• W2163749351 hasConcept C98960154 @default.
• W2163749351 hasConceptScore W2163749351C105795698 @default.
• W2163749351 hasConceptScore W2163749351C116915560 @default.
• W2163749351 hasConceptScore W2163749351C120665830 @default.
• W2163749351 hasConceptScore W2163749351C121332964 @default.
• W2163749351 hasConceptScore W2163749351C127413603 @default.
• W2163749351 hasConceptScore W2163749351C161694136 @default.
• W2163749351 hasConceptScore W2163749351C185544564 @default.
• W2163749351 hasConceptScore W2163749351C192562407 @default.
• W2163749351 hasConceptScore W2163749351C19499675 @default.
• W2163749351 hasConceptScore W2163749351C2779751349 @default.
• W2163749351 hasConceptScore W2163749351C2780330291 @default.
• W2163749351 hasConceptScore W2163749351C2989005 @default.
• W2163749351 hasConceptScore W2163749351C33923547 @default.
• W2163749351 hasConceptScore W2163749351C39432304 @default.
• W2163749351 hasConceptScore W2163749351C41008148 @default.
• W2163749351 hasConceptScore W2163749351C71924100 @default.
• W2163749351 hasConceptScore W2163749351C94915269 @default.
• W2163749351 hasConceptScore W2163749351C98960154 @default.
• W2163749351 hasIssue "1" @default.
• W2163749351 hasLocation W21637493511 @default.
• W2163749351 hasOpenAccess W2163749351 @default.
• W2163749351 hasPrimaryLocation W21637493511 @default.
• W2163749351 hasRelatedWork W1992759751 @default.
• W2163749351 hasRelatedWork W2163749351 @default.
• W2163749351 hasRelatedWork W2278404601 @default.

• next