FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163755879> ?p ?o ?g. }

• W2163755879 endingPage "200" @default.
• W2163755879 startingPage "1193" @default.
• W2163755879 abstract "The aim of this study was to evaluate whether there is a correlation between peripheral blood expression of angiogenic transcriptional factors/receptors and colorectal cancer (CRC).Eighty six blood samples collected from patients with CRC (N=42), adenomas and/or hyperplastic polyps(AP, N=30) and individuals without colon pathology (control group/CTR, N=14) were used for this study. Twelve transcription factors and receptors were assessed by qRT-PCR in a case-control study. The molecules with a minimum of 30% differences in gene expression for CRC and AP compared to CTR were then analyzed separately for each sample. Gene expression was evaluated relatively to the CTR after normalization to the large ribosomal protein PO (RPLPO) housekeeping gene, and the differential expression between studied groups was assessed by ANOVA.Seven out of 12 genes presented differences in expression between 10-29% in CRC and/or AP compared to CTR. Considering the selection criteria, we further individually evaluated the levels of expression of 5 genes that had a minimum of 30% expression in the case-control study. Our data showed a significant up-regulation of platelet derived growth factor (PDGF) C in the blood of the patients with CRC compared to CTR (p=0.007). Likewise, clusterin (CLU) was significantly up-regulated both in CRC and AP groups compared to healthy subjects (p=0.01). For VEGFR1, PDGFRA and TGFB1 we didn't find significantly differential expression between any of the studied groups, even if increased levels were observed in both CRC and AP vs CTR.The results of our study indicated that increased blood level of PDGFC mRNA was associated with the presence of CRC (p=0.007). Additionally, high levels of circulating CLU mRNA were observed in both malignant and benign colorectal pathologies." @default.
• W2163755879 created "2016-06-24" @default.
• W2163755879 creator A5000303021 @default.
• W2163755879 creator A5006938622 @default.
• W2163755879 creator A5022708194 @default.
• W2163755879 creator A5027897849 @default.
• W2163755879 creator A5030604380 @default.
• W2163755879 creator A5030831933 @default.
• W2163755879 creator A5039449589 @default.
• W2163755879 creator A5041368772 @default.
• W2163755879 creator A5042894787 @default.
• W2163755879 creator A5055266198 @default.
• W2163755879 creator A5064374408 @default.
• W2163755879 creator A5064432473 @default.
• W2163755879 creator A5069044777 @default.
• W2163755879 creator A5076787385 @default.
• W2163755879 creator A5081735934 @default.
• W2163755879 creator A5088377932 @default.
• W2163755879 date "2015-11-06" @default.
• W2163755879 modified "2023-10-18" @default.
• W2163755879 title "Is there a correlation between peripheral blood expression of angiogenic transcriptional factors/receptors and colorectal cancer?" @default.
• W2163755879 cites W146419586 @default.
• W2163755879 cites W1483697177 @default.
• W2163755879 cites W1516386979 @default.
• W2163755879 cites W1528666813 @default.
• W2163755879 cites W1723094461 @default.
• W2163755879 cites W1963924501 @default.
• W2163755879 cites W1986406665 @default.
• W2163755879 cites W1991719268 @default.
• W2163755879 cites W1992112921 @default.
• W2163755879 cites W2002029439 @default.
• W2163755879 cites W2006067741 @default.
• W2163755879 cites W2014148719 @default.
• W2163755879 cites W2015634560 @default.
• W2163755879 cites W2019893869 @default.
• W2163755879 cites W2025395607 @default.
• W2163755879 cites W2025894230 @default.
• W2163755879 cites W2026340235 @default.
• W2163755879 cites W2033441741 @default.
• W2163755879 cites W2036260794 @default.
• W2163755879 cites W2037764974 @default.
• W2163755879 cites W2051011980 @default.
• W2163755879 cites W2066524125 @default.
• W2163755879 cites W2074978845 @default.
• W2163755879 cites W2076828545 @default.
• W2163755879 cites W2081107312 @default.
• W2163755879 cites W2088612710 @default.
• W2163755879 cites W2091162444 @default.
• W2163755879 cites W2098985630 @default.
• W2163755879 cites W2100068901 @default.
• W2163755879 cites W2105696702 @default.
• W2163755879 cites W2109560931 @default.
• W2163755879 cites W2110768886 @default.
• W2163755879 cites W2111775556 @default.
• W2163755879 cites W2117692326 @default.
• W2163755879 cites W2126336330 @default.
• W2163755879 cites W2127851171 @default.
• W2163755879 cites W2135343701 @default.
• W2163755879 cites W2151178480 @default.
• W2163755879 cites W2160108544 @default.
• W2163755879 cites W2164279346 @default.
• W2163755879 cites W2171595654 @default.
• W2163755879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26537064" @default.
• W2163755879 hasPublicationYear "2015" @default.
• W2163755879 type Work @default.
• W2163755879 sameAs 2163755879 @default.
• W2163755879 citedByCount "6" @default.
• W2163755879 countsByYear W21637558792017 @default.
• W2163755879 countsByYear W21637558792018 @default.
• W2163755879 crossrefType "journal-article" @default.
• W2163755879 hasAuthorship W2163755879A5000303021 @default.
• W2163755879 hasAuthorship W2163755879A5006938622 @default.
• W2163755879 hasAuthorship W2163755879A5022708194 @default.
• W2163755879 hasAuthorship W2163755879A5027897849 @default.
• W2163755879 hasAuthorship W2163755879A5030604380 @default.
• W2163755879 hasAuthorship W2163755879A5030831933 @default.
• W2163755879 hasAuthorship W2163755879A5039449589 @default.
• W2163755879 hasAuthorship W2163755879A5041368772 @default.
• W2163755879 hasAuthorship W2163755879A5042894787 @default.
• W2163755879 hasAuthorship W2163755879A5055266198 @default.
• W2163755879 hasAuthorship W2163755879A5064374408 @default.
• W2163755879 hasAuthorship W2163755879A5064432473 @default.
• W2163755879 hasAuthorship W2163755879A5069044777 @default.
• W2163755879 hasAuthorship W2163755879A5076787385 @default.
• W2163755879 hasAuthorship W2163755879A5081735934 @default.
• W2163755879 hasAuthorship W2163755879A5088377932 @default.
• W2163755879 hasConcept C104317684 @default.
• W2163755879 hasConcept C121608353 @default.
• W2163755879 hasConcept C126322002 @default.
• W2163755879 hasConcept C143998085 @default.
• W2163755879 hasConcept C150194340 @default.
• W2163755879 hasConcept C16685009 @default.
• W2163755879 hasConcept C170493617 @default.
• W2163755879 hasConcept C190283241 @default.
• W2163755879 hasConcept C2779476363 @default.
• W2163755879 hasConcept C33922130 @default.
• W2163755879 hasConcept C526805850 @default.
• W2163755879 hasConcept C54355233 @default.

• next