FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163855816> ?p ?o ?g. }

• W2163855816 endingPage "2387" @default.
• W2163855816 startingPage "2379" @default.
• W2163855816 abstract "Cachexia is characterized as an inflammatory state induced by the cancer environment, which is accompanied by the loss of muscle and fat mass. Well-investigated mechanisms of cachexia include the suppression of myofiber protein synthesis and the induction of the protein degradation. However, it is not well characterized whether chronic inflammation during cachexia induces myofiber degeneration, which contributes to muscle mass loss and decreased functional capacity. The purpose of this study was to determine whether ApcMin/+ mice, which demonstrate a chronic systemic inflammatory state due to an intestinal tumor burden, undergo cachexia and whether the myofibers exhibit signs of degeneration and/or regeneration. Six-month-old female ApcMin/+ body weight decreased 21% compared with C57BL/6 mice and was not the result of blunted growth. ApcMin/+ gastrocnemius muscle was reduced 45%, and soleus mean fiber cross-sectional area decreased 24% vs. C57BL/6 mice. Soleus muscle morphology demonstrated pathology of myofibers undergoing degeneration and/or regeneration. These data demonstrate that the ApcMin/+ mouse becomes cachectic by 6 mo of age and that skeletal muscle degeneration and regeneration may be related to the muscle loss." @default.
• W2163855816 created "2016-06-24" @default.
• W2163855816 creator A5006785946 @default.
• W2163855816 creator A5029289236 @default.
• W2163855816 creator A5052344963 @default.
• W2163855816 creator A5065128124 @default.
• W2163855816 date "2005-12-01" @default.
• W2163855816 modified "2023-10-09" @default.
• W2163855816 title "Myofiber degeneration/regeneration is induced in the cachectic<i>Apc</i>^<i>Min/+</i>mouse" @default.
• W2163855816 cites W191793640 @default.
• W2163855816 cites W1968444800 @default.
• W2163855816 cites W1979618971 @default.
• W2163855816 cites W1985534077 @default.
• W2163855816 cites W1987051234 @default.
• W2163855816 cites W1995201350 @default.
• W2163855816 cites W2005539179 @default.
• W2163855816 cites W2007628010 @default.
• W2163855816 cites W2008869575 @default.
• W2163855816 cites W2009701222 @default.
• W2163855816 cites W2014316307 @default.
• W2163855816 cites W2016675620 @default.
• W2163855816 cites W2017429680 @default.
• W2163855816 cites W2025896399 @default.
• W2163855816 cites W2027353671 @default.
• W2163855816 cites W2028358008 @default.
• W2163855816 cites W2034269086 @default.
• W2163855816 cites W2039266532 @default.
• W2163855816 cites W2042470379 @default.
• W2163855816 cites W2053830214 @default.
• W2163855816 cites W2055535789 @default.
• W2163855816 cites W2059248106 @default.
• W2163855816 cites W2061114783 @default.
• W2163855816 cites W2068474470 @default.
• W2163855816 cites W2075978435 @default.
• W2163855816 cites W2088477747 @default.
• W2163855816 cites W2106727438 @default.
• W2163855816 cites W2108299127 @default.
• W2163855816 cites W2109355862 @default.
• W2163855816 cites W2121311831 @default.
• W2163855816 cites W2124699186 @default.
• W2163855816 cites W2134617842 @default.
• W2163855816 cites W2138320433 @default.
• W2163855816 cites W2140965132 @default.
• W2163855816 cites W2148625376 @default.
• W2163855816 cites W2151969751 @default.
• W2163855816 cites W2167033587 @default.
• W2163855816 cites W2169448756 @default.
• W2163855816 cites W2170313716 @default.
• W2163855816 cites W2314203153 @default.
• W2163855816 cites W4243087978 @default.
• W2163855816 cites W4293247451 @default.
• W2163855816 cites W96614748 @default.
• W2163855816 doi "https://doi.org/10.1152/japplphysiol.00778.2005" @default.
• W2163855816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16288100" @default.
• W2163855816 hasPublicationYear "2005" @default.
• W2163855816 type Work @default.
• W2163855816 sameAs 2163855816 @default.
• W2163855816 citedByCount "62" @default.
• W2163855816 countsByYear W21638558162012 @default.
• W2163855816 countsByYear W21638558162013 @default.
• W2163855816 countsByYear W21638558162014 @default.
• W2163855816 countsByYear W21638558162015 @default.
• W2163855816 countsByYear W21638558162016 @default.
• W2163855816 countsByYear W21638558162017 @default.
• W2163855816 countsByYear W21638558162018 @default.
• W2163855816 countsByYear W21638558162019 @default.
• W2163855816 countsByYear W21638558162020 @default.
• W2163855816 countsByYear W21638558162021 @default.
• W2163855816 countsByYear W21638558162022 @default.
• W2163855816 countsByYear W21638558162023 @default.
• W2163855816 crossrefType "journal-article" @default.
• W2163855816 hasAuthorship W2163855816A5006785946 @default.
• W2163855816 hasAuthorship W2163855816A5029289236 @default.
• W2163855816 hasAuthorship W2163855816A5052344963 @default.
• W2163855816 hasAuthorship W2163855816A5065128124 @default.
• W2163855816 hasConcept C121608353 @default.
• W2163855816 hasConcept C126322002 @default.
• W2163855816 hasConcept C134018914 @default.
• W2163855816 hasConcept C142724271 @default.
• W2163855816 hasConcept C171056886 @default.
• W2163855816 hasConcept C207200792 @default.
• W2163855816 hasConcept C2775872116 @default.
• W2163855816 hasConcept C2776104385 @default.
• W2163855816 hasConcept C2776214593 @default.
• W2163855816 hasConcept C2776914184 @default.
• W2163855816 hasConcept C2777704314 @default.
• W2163855816 hasConcept C2779354088 @default.
• W2163855816 hasConcept C2779764123 @default.
• W2163855816 hasConcept C2779959927 @default.
• W2163855816 hasConcept C511355011 @default.
• W2163855816 hasConcept C544821477 @default.
• W2163855816 hasConcept C71924100 @default.
• W2163855816 hasConcept C86803240 @default.
• W2163855816 hasConcept C95444343 @default.
• W2163855816 hasConceptScore W2163855816C121608353 @default.
• W2163855816 hasConceptScore W2163855816C126322002 @default.
• W2163855816 hasConceptScore W2163855816C134018914 @default.
• W2163855816 hasConceptScore W2163855816C142724271 @default.

• next