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- W2163923038 abstract "An HPLC method is described using octadecylsilica (3 microns) with an acetonitrile phosphate buffer mobile phase containing diethylamine which is capable of separating ketoconazole [(+/-)-cis-1-acetyl-4-(4[2-(dichlorophenyl)-2- (1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl)pi perazine] from four related compounds, (R049223, R063600, R053165 and R039519) and from excipients in tablets, cream and shampoo. The method was validated using an external calibration method for tablets, shampoo and creams and a standard addition method for cream. The limits of detection for the related compounds in the presence of ketoconazole are also reported." @default.
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- W2163923038 date "1999-01-01" @default.
- W2163923038 modified "2023-09-27" @default.
- W2163923038 title "An HPLC assay for the determination of ketoconazole in common pharmaceutical preparations" @default.
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- W2163923038 doi "https://doi.org/10.1039/a907400g" @default.
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