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• W2163966189 abstract "Combination chemoprevention is a promising approach for oral cancer prevention. The authors evaluated the combined chemopreventive effects of bovine milk lactoferrin (bLF) and black tea polyphenols (Polyphenon-B) in a clinically relevant in vivo model of 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch (HBP) carcinogenesis. Although dietary administration of bLF and Polyphenon-B alone significantly reduced the tumor incidence, combined administration of bLF and polyphenon-B was more effective in inhibiting DMBA-induced genotoxicity and development of HBP carcinomas by modulation of carcinogen-metabolizing enzymes and cellular redox status. These results suggest that a “designer item” approach will be useful for human oral cancer prevention strategies." @default.
• W2163966189 created "2016-06-24" @default.
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• W2163966189 date "2008-01-01" @default.
• W2163966189 modified "2023-09-28" @default.
• W2163966189 title "Combination Chemoprevention of Hamster Buccal Pouch Carcinogenesis by Bovine Milk Lactoferrin and Black Tea Polyphenols" @default.
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• W2163966189 doi "https://doi.org/10.1080/07357900701511961" @default.
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