Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163977553> ?p ?o ?g. }
- W2163977553 abstract "The healthy heart relies primarily upon the oxidation of fatty acids for energy, with the remaining coming from the oxidation of glucose and lactate. Changes in energy requirements are met by altering the balance of fuels depending upon the hormonal milieu as well as upon the availability of oxygen and substrates. The use of carbohydrates for fuel is metabolically more efficient and may improve the coupling between glycolysis and pyruvate oxidation. Therefore, promoting a shift in metabolic fuel substrate use during times of reduced oxygen availability may represent a cardioprotective strategy. Subsequently, there has been interest in pharmacologic strategies such insulin or drugs like ranolazine and dichloroacetate that stimulate carbohydrate oxidation either by enhancing oxidation at the pyruvate dehydrogenase complex or by limiting fatty acid oxidation. There is evidence that nutrients may also be able to stimulate carbohydrate oxidation. Previous studies by our group suggest that a combination of nutrients (carnitine, coenzyme Q10, and taurine) may work together, resulting in pleiotropic cardioprotective effects. Our current studies are investigating the potential of nutrients as both a preventative and adjunctive treatment before and after an ischemic event. These investigations will determine the role of nutritional supplementation in the care of patients with ischemic injury." @default.
- W2163977553 created "2016-06-24" @default.
- W2163977553 creator A5035612714 @default.
- W2163977553 creator A5064608543 @default.
- W2163977553 date "2005-06-01" @default.
- W2163977553 modified "2023-09-27" @default.
- W2163977553 title "Myocardial Metabolism and Improved OutcomesAfter High Risk Heart Surgery" @default.
- W2163977553 cites W1483108854 @default.
- W2163977553 cites W1497976031 @default.
- W2163977553 cites W1525616846 @default.
- W2163977553 cites W1528838750 @default.
- W2163977553 cites W1541324572 @default.
- W2163977553 cites W1573788449 @default.
- W2163977553 cites W1775658716 @default.
- W2163977553 cites W1867252638 @default.
- W2163977553 cites W1967600689 @default.
- W2163977553 cites W1969833131 @default.
- W2163977553 cites W1972516159 @default.
- W2163977553 cites W1977741433 @default.
- W2163977553 cites W1986571045 @default.
- W2163977553 cites W1992422382 @default.
- W2163977553 cites W2004973491 @default.
- W2163977553 cites W2011315228 @default.
- W2163977553 cites W2015991505 @default.
- W2163977553 cites W2016658587 @default.
- W2163977553 cites W2020565338 @default.
- W2163977553 cites W2040753650 @default.
- W2163977553 cites W2045002427 @default.
- W2163977553 cites W2048228597 @default.
- W2163977553 cites W2064301374 @default.
- W2163977553 cites W2065077168 @default.
- W2163977553 cites W2066707405 @default.
- W2163977553 cites W2067117451 @default.
- W2163977553 cites W2068948766 @default.
- W2163977553 cites W2073216357 @default.
- W2163977553 cites W2079171902 @default.
- W2163977553 cites W2084985537 @default.
- W2163977553 cites W2089405170 @default.
- W2163977553 cites W2093341858 @default.
- W2163977553 cites W2107750788 @default.
- W2163977553 cites W2114445117 @default.
- W2163977553 cites W2128494948 @default.
- W2163977553 cites W2136879982 @default.
- W2163977553 cites W2137629569 @default.
- W2163977553 cites W2145928544 @default.
- W2163977553 cites W2166868657 @default.
- W2163977553 cites W2169893832 @default.
- W2163977553 cites W2278611370 @default.
- W2163977553 cites W2399949167 @default.
- W2163977553 cites W2780668190 @default.
- W2163977553 cites W66473082 @default.
- W2163977553 doi "https://doi.org/10.1177/108925320500900212" @default.
- W2163977553 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15920644" @default.
- W2163977553 hasPublicationYear "2005" @default.
- W2163977553 type Work @default.
- W2163977553 sameAs 2163977553 @default.
- W2163977553 citedByCount "1" @default.
- W2163977553 crossrefType "journal-article" @default.
- W2163977553 hasAuthorship W2163977553A5035612714 @default.
- W2163977553 hasAuthorship W2163977553A5064608543 @default.
- W2163977553 hasConcept C126322002 @default.
- W2163977553 hasConcept C17093226 @default.
- W2163977553 hasConcept C181199279 @default.
- W2163977553 hasConcept C185592680 @default.
- W2163977553 hasConcept C20251656 @default.
- W2163977553 hasConcept C2778004101 @default.
- W2163977553 hasConcept C2994476132 @default.
- W2163977553 hasConcept C55493867 @default.
- W2163977553 hasConcept C62231903 @default.
- W2163977553 hasConcept C71924100 @default.
- W2163977553 hasConcept C82714985 @default.
- W2163977553 hasConcept C88099638 @default.
- W2163977553 hasConceptScore W2163977553C126322002 @default.
- W2163977553 hasConceptScore W2163977553C17093226 @default.
- W2163977553 hasConceptScore W2163977553C181199279 @default.
- W2163977553 hasConceptScore W2163977553C185592680 @default.
- W2163977553 hasConceptScore W2163977553C20251656 @default.
- W2163977553 hasConceptScore W2163977553C2778004101 @default.
- W2163977553 hasConceptScore W2163977553C2994476132 @default.
- W2163977553 hasConceptScore W2163977553C55493867 @default.
- W2163977553 hasConceptScore W2163977553C62231903 @default.
- W2163977553 hasConceptScore W2163977553C71924100 @default.
- W2163977553 hasConceptScore W2163977553C82714985 @default.
- W2163977553 hasConceptScore W2163977553C88099638 @default.
- W2163977553 hasLocation W21639775531 @default.
- W2163977553 hasLocation W21639775532 @default.
- W2163977553 hasOpenAccess W2163977553 @default.
- W2163977553 hasPrimaryLocation W21639775531 @default.
- W2163977553 hasRelatedWork W102025076 @default.
- W2163977553 hasRelatedWork W1977726249 @default.
- W2163977553 hasRelatedWork W1990291053 @default.
- W2163977553 hasRelatedWork W1990485158 @default.
- W2163977553 hasRelatedWork W2022143285 @default.
- W2163977553 hasRelatedWork W2024035381 @default.
- W2163977553 hasRelatedWork W203203910 @default.
- W2163977553 hasRelatedWork W2215901665 @default.
- W2163977553 hasRelatedWork W2444155228 @default.
- W2163977553 hasRelatedWork W3190508667 @default.
- W2163977553 isParatext "false" @default.
- W2163977553 isRetracted "false" @default.