FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2164067110> ?p ?o ?g. }

• W2164067110 abstract "We read the article by Knopp et al about endoscopic findings in patients after radiofrequency ablation (RFA) of atrial fibrillation (AF) with interest. Gastrointestinal abnormalities were detected by using esophagogastroduodenoscopy (EGD) in 77% (327 of 425) patients 1–3 days after RFA. Since EGD was carried out only after RFA, the following could not be assessed: how many of these abnormalities were indeed the direct consequence of RFA, and how many were already present before RFA and contributed to the pathogenesis of AF. How many of the 327 patients with lesions on EGD received proton-pump inhibitors or H2 blockers before RFA? An association of gastroesophageal reflux disease (GERD) with AF is suggested by clinical and epidemiological studies. One pathomechanism of AF in GERD may be local inflammation penetrating the esophageal wall and thus affecting the adjacent vagal nerves. The innervation of the esophageal mucosa is altered in response to inflammation. Inflammation of the esophageal mucosa may trigger afferent-efferent reflex mechanisms with involvement of the cerebral representation of cardiac modalities and thus lead to secondary affection of the vagal nerves. In addition, GERD may lead to a release of inflammatory mediators or to an autoimmune response, which may affect the atrial myocardium or the cardiac conduction system. Thus, it would be of interest if the included patients with gastroesophageal abnormalities had a higher recurrence rate of AF after RFA than did patients with normal EGD findings. How was gastroparesis defined, and how was regression of gastroparesis diagnosed during follow-up? Based on which observations do the authors conclude that gastroparesis can be attributed to RFA when they do not have evidence for gastroparesis before RFA? Gastroparesis may be multicausal including vagal denervation or direct affection of smooth muscle cells. Were there any patients who developed atrioesophageal fistula during the recruitment period? Did these patients show any abnormalities at EGD? Patients with AF frequently receive oral anticoagulant drugs, and some of them, such as dabigatran, are known to have gastrointestinal side effects. Was there any association between the type of anticoagulant drugs between patients with and without gastrointestinal abnormalities? Many patients with AF develop stroke/embolism. Was there a difference in the frequency of EGD abnormalities between those with and without a previous stroke/embolism? AF may be due to cardiac involvement in a neuromuscular disorder. How many of the patients undergoing RFA had a muscle disease? In conclusion, more data about the complex relationship between the esophagus, the left atrium, and its nerval connections are necessary." @default.
• W2164067110 created "2016-06-24" @default.
• W2164067110 creator A5029331446 @default.
• W2164067110 creator A5058779655 @default.
• W2164067110 date "2014-09-01" @default.
• W2164067110 modified "2023-09-26" @default.
• W2164067110 title "To the Editor—Left atrium, vagal nerve, and esophagus: A neighborhood with close relations" @default.
• W2164067110 cites W1565058259 @default.
• W2164067110 cites W1967355934 @default.
• W2164067110 cites W1991804894 @default.
• W2164067110 cites W2105106824 @default.
• W2164067110 cites W2136139394 @default.
• W2164067110 doi "https://doi.org/10.1016/j.hrthm.2014.05.030" @default.
• W2164067110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24879952" @default.
• W2164067110 hasPublicationYear "2014" @default.
• W2164067110 type Work @default.
• W2164067110 sameAs 2164067110 @default.
• W2164067110 citedByCount "1" @default.
• W2164067110 countsByYear W21640671102014 @default.
• W2164067110 crossrefType "journal-article" @default.
• W2164067110 hasAuthorship W2164067110A5029331446 @default.
• W2164067110 hasAuthorship W2164067110A5058779655 @default.
• W2164067110 hasConcept C126322002 @default.
• W2164067110 hasConcept C141071460 @default.
• W2164067110 hasConcept C164705383 @default.
• W2164067110 hasConcept C24998067 @default.
• W2164067110 hasConcept C2776131983 @default.
• W2164067110 hasConcept C2777014526 @default.
• W2164067110 hasConcept C2777819096 @default.
• W2164067110 hasConcept C2778451229 @default.
• W2164067110 hasConcept C2778769438 @default.
• W2164067110 hasConcept C2779134260 @default.
• W2164067110 hasConcept C2779161974 @default.
• W2164067110 hasConcept C2779422922 @default.
• W2164067110 hasConcept C2779920096 @default.
• W2164067110 hasConcept C2780596822 @default.
• W2164067110 hasConcept C2781143854 @default.
• W2164067110 hasConcept C2781404750 @default.
• W2164067110 hasConcept C3020479747 @default.
• W2164067110 hasConcept C43270747 @default.
• W2164067110 hasConcept C71924100 @default.
• W2164067110 hasConcept C90924648 @default.
• W2164067110 hasConceptScore W2164067110C126322002 @default.
• W2164067110 hasConceptScore W2164067110C141071460 @default.
• W2164067110 hasConceptScore W2164067110C164705383 @default.
• W2164067110 hasConceptScore W2164067110C24998067 @default.
• W2164067110 hasConceptScore W2164067110C2776131983 @default.
• W2164067110 hasConceptScore W2164067110C2777014526 @default.
• W2164067110 hasConceptScore W2164067110C2777819096 @default.
• W2164067110 hasConceptScore W2164067110C2778451229 @default.
• W2164067110 hasConceptScore W2164067110C2778769438 @default.
• W2164067110 hasConceptScore W2164067110C2779134260 @default.
• W2164067110 hasConceptScore W2164067110C2779161974 @default.
• W2164067110 hasConceptScore W2164067110C2779422922 @default.
• W2164067110 hasConceptScore W2164067110C2779920096 @default.
• W2164067110 hasConceptScore W2164067110C2780596822 @default.
• W2164067110 hasConceptScore W2164067110C2781143854 @default.
• W2164067110 hasConceptScore W2164067110C2781404750 @default.
• W2164067110 hasConceptScore W2164067110C3020479747 @default.
• W2164067110 hasConceptScore W2164067110C43270747 @default.
• W2164067110 hasConceptScore W2164067110C71924100 @default.
• W2164067110 hasConceptScore W2164067110C90924648 @default.
• W2164067110 hasLocation W21640671101 @default.
• W2164067110 hasLocation W21640671102 @default.
• W2164067110 hasOpenAccess W2164067110 @default.
• W2164067110 hasPrimaryLocation W21640671101 @default.
• W2164067110 hasRelatedWork W1992753622 @default.
• W2164067110 hasRelatedWork W2059062976 @default.
• W2164067110 hasRelatedWork W222460400 @default.
• W2164067110 hasRelatedWork W2322900513 @default.
• W2164067110 hasRelatedWork W2412113433 @default.
• W2164067110 hasRelatedWork W2417304895 @default.
• W2164067110 hasRelatedWork W2432674891 @default.
• W2164067110 hasRelatedWork W2435528752 @default.
• W2164067110 hasRelatedWork W3141700921 @default.
• W2164067110 hasRelatedWork W4249523386 @default.
• W2164067110 isParatext "false" @default.
• W2164067110 isRetracted "false" @default.
• W2164067110 magId "2164067110" @default.
• W2164067110 workType "article" @default.