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- W2164259251 abstract "Previous results showed that an indigenously isolated yeast strain of Candida tropicalis was found to produce 12.11 g/L of xylitol under unoptimized conditions in presence of 50 g/L of xylose. In the present study, optimizing the process using one-variable at-a-time resulted in the production of 59.07 g/L of xylitol in 96 h in presence of 100 g/L xylose. Further optimization using response surface methodology led to the production of 65.45 g/L in medium containing 100 g/L xylose, 0.5% yeast extract, 0.03% MgSO 4 .7H 2 O and 0.2% KH 2 PO 4 , pH-4.5, 30 °C, 200 r/min for 96 h with 4% inoculum level. Addition of 1% methanol in response surface methodology optimized–medium led to the production of 67.12 g/L. Scaling up in 10 L fermentor resulted in productivity of 0.80 g/Lh with yield of 0.68 g/g. Efficient synthesis of xylitol esters was achieved with butyric acid (50.32%) and caproic acid (38.36%) in 4 h using Pseudomonas aeruginosa lipase in t-butanol: tetrahydrofuran (1:1 v/v)." @default.
- W2164259251 created "2016-06-24" @default.
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- W2164259251 date "2013-06-03" @default.
- W2164259251 modified "2023-10-12" @default.
- W2164259251 title "Statistical approach to study the interactive effects of process parameters for enhanced xylitol production by <i>Candida tropicalis</i> and its potential for the synthesis of xylitol monoesters" @default.
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- W2164259251 doi "https://doi.org/10.1177/1082013212462230" @default.
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